
Prof. Dr.-Ing. Laura De Laporte
Laura De Laporte develops biohybrid and bioinspired materials for advanced medical applications, for example to replicate the complex structure of natural tissues. To achieve this, she is working on new synthetic material concepts and new methods of manufacture, combining engineering, chemistry and biology to design biomaterials that control and direct the interaction with cells. Her team designs low-invasive, polymeric regenerative hydrogel therapies, consisting of nano –and micron-scale building blocks that orient after injection to repair anisotropic tissues, such as the spinal cord. In addition, dynamic hydrogels are created for drug delivery and to study mechanobiology.
Resume
Laura De Laporte studied chemical engineering at Ghent University (Belgium). She received her PhD from Northwestern University (Evanston, USA) in the group of Prof. Lonnie Shea, where she developed guided implants for nerve regeneration. At EPFL (Lausanne, Switzerland), she researched regenerative hydrogels in the group of Prof. Jeffrey Hubbell. From 2013 to 2018, Laura De Laporte led a junior research group at DWI – Leibniz Institute for Interactive Materials in Aachen and was awarded a Starting Grant from the European Research Council in 2015. In October 2017, she completed her habilitation at the Department of Chemistry of RWTH Aachen University. In 2018, she was one of five excellent female researchers who have received funding from the Leibniz Programme for female Professors and became an associate professor in the Chemistry Department with the teaching and research area Advanced Materials for Biomedicine. Since 2021, she is also part of the Institute for Applied Medical Engineering and affiliated to the University Hospital RWTH Aachen. In 2022, De Laporte received an ERC Consolidator Grant for the "Heartbeat" project. Since November 2024, she is head of the Chair of Macromolecular Materials for Medicine at RWTH Aachen University.
Selected professional functions, honors and awards
- Since 2021 Board of International Society of Biofabrication (ISBF)
- 2020-2021 Associated Editor ACS Applied Materials and Interfaces
- Since 2020 Editorial Advisory Board Advanced Healthcare Materials
- 2019 Steinhofer Lecture
- 2018 Young Investigator Award - Engineering Conferences International
- 2016 Max Buchner Research Foundation
- 2008–2009 Terminal Year Richter Fellowship, Northwestern University
- 2008 AIChE Women's Initiatives Committee Travel Award, USA
- 2006-2008 Conference Travel Grant, Northwestern University (annual)
- 2006 CGM Travel Fellowship Award, USA
- 2004–2005 International Doctoral Fellowship, Northwestern University
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Cellular responses to beating hydrogels to investigate mechanotransduction
Y. Chandorkar, A. Castro Nava, S. Schweizerhof, M. Van Dongen, T. Haraszti, J. Köhler, H. Zhang, R. Windoffer, A. Mourran, M. Möller, L. De Laporte
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https://doi.org/10.1038/s41467-019-11475-4 | Nature Communications | 2019 | |
Compartmentalized Jet Polymerization as a High-Resolution Process to Continuously Produce Anisometric Microgel Rods with Adjustable Size and Stiffness
A. J. D. Krüger, O. Bakirman, L. P. B. Guerzoni, A. Jans, D. B. Gehlen, D. Rommel, T. Haraszti, A. J. C. Kuehne, L. De Laporte
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https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201903668 | Advanced Materials | 2019 | |
High-Throughput Production of Micrometer Sized Double Emulsions and Microgel Capsules in Parallelized 3D Printed Microfluidic Devices
A. Jans, J. Lolsberg, A. Omidinia-Anarkoli, R. Viermann, M. Möller, L. De Laporte, M. Wessling and A. J. C. Kühne
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https://www.doi.org/10.3390/polym11111887 | Polymers | 2019 | |
Metal-Organic Gels Based on a Bisamide Tetracarboxyl Ligand for Carbon Dioxide, Sulfur Dioxide, and Selective Dye Uptake
D. Dietrich, C. Licht, A. Nuhnen, S. P. Hofert, L. De Laporte and C. Janiak
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https://pubs.acs.org/doi/full/10.1021/acsami.9b04659 | ACS Applied Materials & Interfaces | 2019 | |
Nanofibrillar Cellulose as an Enzymatically and Flow Driven Degradable Scaffold for 3D Tissue Engineering
M. Krüger, B. Spee, A. Walther, L. De Laporte. L.M. Kock
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https://doi.org/10.1115/1.4044473 | Journal of Engineering and Science in Medical Diagnostics and Therapy | 2019 | |
Predicting the orientation of magnetic microgel rods for soft anisotropic biomimetic hydrogels
J. C. Rose, M. Fölster, L. Kivilip, J. L. Gerardo-Nava, E. E. Jaekel, D. B. Gehlen, W. Rohlfs and L. De Laporte
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https://doi.org/10.1039/C9PY01008D | Polymer Chemistry | 2019 | |
Rapid and Robust Coating Method to Render Polydimethylsiloxane Surfaces Cell-Adhesive
D. B. Gehlen, L. C. De Lencastre Novaes, W. Long, A. J. Ruff, F. Jakob, T. Haraszti, Y. Chandorkar, L. Yang, P. van Rijn, U. Schwaneberg and L. De Laporte
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https://www.doi.org/10.1021/acsami.9b16025 | ACS Appl Mater Interfaces | 2019 | |
Soft temperature-responsive microgels of complex shape in stop-flow lithography
H. J. M. Wolff, J. Linkhorst, T. Göttlich, J. Savinsky, A. J. D. Krüger, L. de Laporte and M. Wessling
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https://doi.org/10.1039/C9LC00749K | Lab on a Chip | 2019 | |
Solvent-Induced Nanotopographies of Single Microfibers Regulate Cell Mechanotransduction
A. Omidinia-Anarkoli, R. Rimal, Y. Chandorkar, D. B. Gehlen, J. C. Rose, K. Rahimi, T. Haraszti and L. De Laporte
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https://www.doi.org/10.1021/acsami.8b17955 | Acs Applied Materials & Interfaces | 2019 | |
Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension
C. Licht, J. C. Rose, A. O. Anarkoli, D. Blondel, M. Roccio, T. Haraszti, D. B. Gehlen, J. A. Hubbell, M. P. Lutolf and L. De Laporte
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https://www.doi.org/10.1021/acs.biomac.9b00891 | Biomacromolecules | 2019 | |
A catalyst-free, temperature controlled gelation system for in-mold fabrication of microgels
A. J. D. Kruger, J. Kohler, S. Cichosz, J. C. Rose, D. B. Gehlen, T. Haraszti, M. Moller and L. De Laporte
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https://www.dwi.rwth-aachen.de/files/redaktion/Publikationen/A%20catalyst-free%2C%20temperature%20controlled%20gelation%20system%20for%20in%20mold%20fabrication%20of%20microgels.pdf | Chemical Communications | 2018 | |
A water-soluble PEGylated RGD-functionalized bisbithiophenyl diketopyrrolopyrrole as a photoacoustic sonophore
T. Repenko, A. Rix, B. Haehnle, W. Lederle, L. De Laporte and A. J. C. Kuehne
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https://www.doi.org/10.1039/c8pp00069g | Photochemical & Photobiological Sciences | 2018 |