Prof. Dr.-Ing. Laura De Laporte
Laura De Laporte develops biohybrid and bioinspired materials for advanced medical applications, for example to replicate the complex structure of natural tissues. To achieve this, she is working on new synthetic material concepts and new methods of manufacture, combining engineering, chemistry and biology to design biomaterials that control and direct the interaction with cells. Her team designs low-invasive, polymeric regenerative hydrogel therapies, consisting of nano –and micron-scale building blocks that orient after injection to repair anisotropic tissues, such as the spinal cord. In addition, dynamic hydrogels are created for drug delivery and to study mechanobiology.
Curriculum Vitae
Laura De Laporte studied chemical engineering at Ghent University (Belgium). She received her PhD from Northwestern University (Evanston, USA) in the group of Prof. Lonnie Shea, where she developed guided implants for nerve regeneration. At EPFL (Lausanne, Switzerland), she researched regenerative hydrogels in the group of Prof. Jeffrey Hubbell. From 2013 to 2018, Laura De Laporte led a junior research group at DWI – Leibniz Institute for Interactive Materials in Aachen and was awarded a Starting Grant from the European Research Council in 2015. In October 2017, she completed her habilitation at the Department of Chemistry of RWTH Aachen University. In 2018, she was one of five excellent female researchers who have received funding from the Leibniz Programme for female Professors and became an associate professor in the Chemistry Department with the teaching and research area Advanced Materials for Biomedicine. Since 2021, she is also part of the Institute for Applied Medical Engineering and affiliated to the University Hospital RWTH Aachen. In 2022, De Laporte received an ERC Consolidator Grant for the "Heartbeat" project.
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Selected professional functions, honors and awards
- Since 2021 Board of International Society of Biofabrication (ISBF)
- 2020-2021 Associated Editor ACS Applied Materials and Interfaces
- Since 2020 Editorial Advisory Board Advanced Healthcare Materials
- 2019 Steinhofer Lecture
- 2018 Young Investigator Award - Engineering Conferences International
- 2016 Max Buchner Research Foundation
- 2008–2009 Terminal Year Richter Fellowship, Northwestern University
- 2008 AIChE Women's Initiatives Committee Travel Award, USA
- 2006-2008 Conference Travel Grant, Northwestern University (annual)
- 2006 CGM Travel Fellowship Award, USA
- 2004–2005 International Doctoral Fellowship, Northwestern University
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Liposome Manufacturing under Continuous Flow Conditions: Towards a Fully Integrated Set-up with in-Line Control of Critical Quality Attributes
M. Sheybanifard, L. P. B. Guerzoni, A. Omidinia-Anarkoli, L. De Laporte, J. Buyel, R. Besseling, M. Damen, A. Gerich, T. Lammers and J. M. Metselaar
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https://doi.org/10.1039/D2LC00463A | Lab on a Chip | 2022 | |
Pre-Programmed Rod-Shaped Microgels to Create Multi-Directional Anisogels for 3d Tissue Engineering
D. L. Braunmiller, S. Babu, D. B. Gehlen, M. Seuß, T. Haraszti, A. Falkenstein, J. Eigen, L. De Laporte and J. J. Crassous
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https://doi.org/10.1002/adfm.202202430 | Advanced Functional Materials | 2022 | |
Anisometric Microstructures to Determine Minimal Critical Physical Cues Required for Neurite Alignment
S. Vedaraman, A. Perez-Tirado, T. Haraszti, J. Gerardo-Nava, A. Nishiguchi and L. De Laporte
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https://doi.org/10.1002/adhm.202100874 | Advanced Healthcare Materials | 2021 | |
Bicyclic RGD peptides enhance nerve growth in synthetic PEG-based Anisogels
S. Vedaraman, D. Bernhagen, T. Haraszti, C. Licht, A. Castro Nava, A. Omidinia Anarkoli, P. Timmerman and L. De Laporte
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https://doi.org/10.1039/D0BM02051F | Biomaterials Science | 2021 | |
Controlling Structure with Injectable Biomaterials to Better Mimic Tissue Heterogeneity and Anisotropy
S. Babu, F. Albertino, A. Omidinia Anarkoli and L. De Laporte
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https://doi.org/10.1002/adhm.202002221 | Advanced Healthcare Materials | 2021 | |
Is the Microgel Collapse a Two-Step Process? Exploiting Cononsolvency to Probe the Collapse Dynamics of Poly-N-isopropylacrylamide (pNIPAM)
K. Nothdurft, D. H. Müller, S. D. Mürtz, A. A. Meyer, L. P. B. Guerzoni, A. Jans, A. J. C. Kühne, L. De Laporte, T. Brands, A. Bardow and W. Richtering
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https://doi.org/10.1021/acs.jpcb.0c10430 | Journal of Physical Chemistry B | 2021 | |
Synergy of Advanced Experimental and Modeling Tools to Underpin the Synthesis of Static Step-Growth-Based Networks Involving Polymeric Precursor Building Blocks
L. De Keer, F. Cavalli, D. Estupiñán, A. J. D. Krüger, S. Rocha, P. H. M. Van Steenberge, M.-F. Reyniers, L. De Laporte, J. Hofkens, L. Barner and D. R. D’hooge
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https://doi.org/10.1021/acs.macromol.1c01476 | Macromolecules | 2021 | |
Translating Therapeutic Microgels into Clinical Applications
Y. Kittel, A. J. C. Kühne and L. De Laporte
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https://doi.org/10.1002/adhm.202101989 | Advanced Healthcare Materials | 2021 | |
Cellulose Nanofibril Hydrogel Promotes Hepatic Differentiation of Human Liver Organoids
M. Kruger, L. A. Oosterhoff, M. E. van Wolferen, S. A. Schiele, A. Walther, N. Geijsen, L. De Laporte, L. J. W. van der Laan, L. M. Kock, B. Spee
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https://doi.org/10.1002/adhm.201901658 | Advanced Healthcare Materials | 2020 | |
Digitally Fabricated and Naturally Augmented In Vitro Tissues
D. F. Duarte Campos and L. De Laporte
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https://doi.org/10.1002/adhm.202001253 | Advanced Healthcare Materials | 2020 | |
Granular Cellulose Nanofibril Hydrogel Scaffolds for 3D Cell Cultivation
D. B. Gehlen, N. Jürgens, A. Omidinia‐Anarkoli, T. Haraszti, J. George, A. Walther, H. Ye and L. De Laporte
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https://doi.org/10.1002/marc.202000191 | Macromolecular Rapid Communications | 2020 | |
Hierarchical fibrous guiding cues at different scales influence linear neurite extension
A. Omidinia-Anarkoli, J. W. Ephraim, R. Rimal and L. De Laporte
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https://doi.org/10.1016/j.actbio.2020.07.014 | Acta Biomaterialia | 2020 |