Multi-functional microgels

In this project, we will develop multifunctional microgels capable of scavenging inflammatory mediators as well as targeting, imaging, and protecting inflamed intestinal tissue. Functionalization of microgel with galectins and adhesion peptides will target the inflamed tissue thereby building a protective microgel layer to prevent secondary bacterial infection. Microgels with scavenging and imaging units will capture the inflammation ligand TNFα and localize at the sites of inflammation. The ultimate goal is to generate therapeutic, diagnostic, and theranostic microgels.