Prof. Dr.-Ing. Laura De Laporte
Laura De Laporte develops biohybrid and bioinspired materials for advanced medical applications, for example to replicate the complex structure of natural tissues. To achieve this, she is working on new synthetic material concepts and new methods of manufacture, combining engineering, chemistry and biology to design biomaterials that control and direct the interaction with cells. Her team designs low-invasive, polymeric regenerative hydrogel therapies, consisting of nano –and micron-scale building blocks that orient after injection to repair anisotropic tissues, such as the spinal cord. In addition, dynamic hydrogels are created for drug delivery and to study mechanobiology.
Curriculum Vitae
Prof. Dr.-Ing. Laura De Laporte is a Chemical Engineer from the University of Ghent (Belgium), where she got the tissue engineering microbe. To follow her dream, she did her PhD with Prof. Lonnie Shea at Northwestern University (Evanston, US) and engineered guiding implants for nerve regeneration. At EPFL (Lausanne, Switzerland), she learned about regenerative hydrogels in Prof. Jeffrey Hubbell’s group during her post-doctoral research. From 2013 to 2018, Laura De Laporte led a junior group at the DWI – Leibniz Institute and was awarded a Starting Grant from the European Research Council in 2015. In October 2017, she finished her Habilitation in the Chemistry Department of the RWTH and has been an associate professor in the same department with an additional affiliation to the University Hospital in Aachen since December 2020. In 2018, she was one of five excellent female researchers who have received funding from the Leibniz Programme for female Professors.
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Selected professional functions, honors and awards
- Since 2021 Board of International Society of Biofabrication (ISBF)
- 2020-2021 Associated Editor ACS Applied Materials and Interfaces
- Since 2020 Editorial Advisory Board Advanced Healthcare Materials
- 2019 Steinhofer Lecture
- 2018 Young Investigator Award - Engineering Conferences International
- 2016 Max Buchner Research Foundation
- 2008–2009 Terminal Year Richter Fellowship, Northwestern University
- 2008 AIChE Women's Initiatives Committee Travel Award, USA
- 2006-2008 Conference Travel Grant, Northwestern University (annual)
- 2006 CGM Travel Fellowship Award, USA
- 2004–2005 International Doctoral Fellowship, Northwestern University
Projects
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Transformative Materials to Create 3D Functional Human Tissue Models in Vitro in a Reproducible Manner
J. L. Gerardo-Nava, J. Jansen, D. Günther, L. Klasen, A. L. Thiebes, B. Niessing, C. Bergerbit, A. A. Meyer, J. Linkhorst, M. Barth, P. Akhyari, J. Stingl, S. Nagel, T. Stiehl, A. Lampert, R. Leube, M. Wessling, F. Santoro, S. Ingebrandt, S. Jockenhoevel, A. Herrmann, H. Fischer, W. Wagner, R. H. Schmitt, F. Kiessling, R. Kramann and L. De Laporte
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https://doi.org/10.1002/adhm.202301030 | Advanced Healthcare Materials | 2023 | |
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Annealing High Aspect Ratio Microgels into Macroporous 3D Scaffolds Allows for Higher Porosities and Effective Cell Migration
A. C. Suturin, A. J. D. Krüger, K. Neidig, N. Klos, N. Dolfen, M. Bund, T. Gronemann, R. Sebers, A. Manukanc, G. Yazdani, Y. Kittel, D. Rommel, T. Haraszti, J. Köhler and L. De Laporte
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https://doi.org/10.1002/adhm.202200989 | Advanced Healthcare Materials | 2022 | |
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Cells Feel the Beat – Temporal Effect of Cyclic Mechanical Actuation on Muscle Cells
Y. Chandorkar, C. Bastard, J. Di Russo, T. Haraszti and L. De Laporte
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https://doi.org/10.1016/j.apmt.2022.101492 | Applied Materials Today | 2022 | |
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Controlled Covalent Self-Assembly of a Homopolymer for Multiscale Materials Engineering
X. Bai, Q. Sun, H. Cui, L. P. B. Guerzoni, S. Wuttke, F. Kiessling, L. De Laporte, T. Lammers and Y. Shi
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https://doi.org/10.1002/adma.202109701 | Advanced Materials | 2022 | |
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ECM-Transmitted Shear Stress Induces Apoptotic Cell Extrusion in Early Breast Gland Development
F. Friedland, S. Babu, R. Springer, J. Konrad, Y. Herfs, S. Gerlach, J. Gehlen, H.-J. Krause, L. De Laporte, R. Merkel and E. Noetzel
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https://doi.org/10.3389/fcell.2022.947430 | Frontiers in Cell and Developmental Biology | 2022 | |
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Engineering the Acoustic Response and Drug Loading Capacity of PBCA-Based Polymeric Microbubbles with Surfactants
R. A. Barmin, A. Dasgupta, C. Bastard, L. De Laporte, S. Rütten, M. Weiler, F. Kiessling, T. Lammers and R. M. Pallares
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https://doi.org/10.1021/acs.molpharmaceut.2c00416 | Molecular Pharmaceutics | 2022 | |
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Enhanced Stable Cavitation and Nonlinear Acoustic Properties of Poly(Butyl Cyanoacrylate) Polymeric Microbubbles after Bioconjugation
R. A. Barmin, A. Dasgupta, A. Rix, M. Weiler, L. Appold, S. Rütten, F. Padilla, A. J. C. Kuehne, A. Pich, L. De Laporte, F. Kiessling, R. M. Pallares and T. Lammers
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https://doi.org/10.1021/acsbiomaterials.2c01021 | ACS Biomaterials Science & Engineering | 2022 | |
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Fabrication of pH-Degradable Supramacromolecular Microgels with Tunable Size and Shape via Droplet-Based Microfluidics
S. H. Jung, S. Bulut, L. P. B. Busca Guerzoni, D. Günther, S. Braun, L. De Laporte and A. Pich
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https://doi.org/10.1016/j.jcis.2022.02.065 | Journal of Colloid and Interface Science | 2022 | |
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Functionalized Microgel Rods Interlinked into Soft Macroporous Structures for 3D Cell Culture
D. Rommel, M. Mork, S. Vedaraman, C. Bastard, L. P. B. Guerzoni, Y. Kittel, R. Vinokur, N. Born, T. Haraszti and L. De Laporte
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https://doi.org/10.1002/advs.202103554 | Advanced Science | 2022 | |
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High Macromolecular Crowding in Liposomes from Microfluidics
L. P. B. Guerzoni, A. V. C. de Goes, M. Kalacheva, J. Haduła, M. Mork, L. De Laporte and A. J. Boersma
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https://doi.org/10.1002/advs.202201169 | Advanced Science | 2022 | |
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How do the Local Physical, Biochemical, and Mechanical Properties of an Injectable Synthetic Anisotropic Hydrogel Affect Oriented Nerve Growth?
S. Babu, I. Chen, S. Vedaraman, J. Gerardo-Nava, C. Licht, Y. Kittel, T. Haraszti, J. Di Russo and L. De Laporte
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https://doi.org/10.1002/adfm.202202468 | Advanced Functional Materials | 2022 | |
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Interlinked Macroporous 3d Scaffolds from Microgel Rods
D. Rommel, S. Vedaraman, M. Mork and L. De Laporte
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https://doi.org/10.3791/64010 | Jove-Journal of Visualized Experiments | 2022 |