Prof. Dr.-Ing. Laura De Laporte
Laura De Laporte develops biohybrid and bioinspired materials for advanced medical applications, for example to replicate the complex structure of natural tissues. To achieve this, she is working on new synthetic material concepts and new methods of manufacture, combining engineering, chemistry and biology to design biomaterials that control and direct the interaction with cells. Her team designs low-invasive, polymeric regenerative hydrogel therapies, consisting of nano –and micron-scale building blocks that orient after injection to repair anisotropic tissues, such as the spinal cord. In addition, dynamic hydrogels are created for drug delivery and to study mechanobiology.
Curriculum Vitae
Laura De Laporte studied chemical engineering at Ghent University (Belgium). She received her PhD from Northwestern University (Evanston, USA) in the group of Prof. Lonnie Shea, where she developed guided implants for nerve regeneration. At EPFL (Lausanne, Switzerland), she researched regenerative hydrogels in the group of Prof. Jeffrey Hubbell. From 2013 to 2018, Laura De Laporte led a junior research group at DWI – Leibniz Institute for Interactive Materials in Aachen and was awarded a Starting Grant from the European Research Council in 2015. In October 2017, she completed her habilitation at the Department of Chemistry of RWTH Aachen University. In 2018, she was one of five excellent female researchers who have received funding from the Leibniz Programme for female Professors and became an associate professor in the Chemistry Department with the teaching and research area Advanced Materials for Biomedicine. Since 2021, she is also part of the Institute for Applied Medical Engineering and affiliated to the University Hospital RWTH Aachen. In 2022, De Laporte received an ERC Consolidator Grant for the "Heartbeat" project.
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Selected professional functions, honors and awards
- Since 2021 Board of International Society of Biofabrication (ISBF)
- 2020-2021 Associated Editor ACS Applied Materials and Interfaces
- Since 2020 Editorial Advisory Board Advanced Healthcare Materials
- 2019 Steinhofer Lecture
- 2018 Young Investigator Award - Engineering Conferences International
- 2016 Max Buchner Research Foundation
- 2008–2009 Terminal Year Richter Fellowship, Northwestern University
- 2008 AIChE Women's Initiatives Committee Travel Award, USA
- 2006-2008 Conference Travel Grant, Northwestern University (annual)
- 2006 CGM Travel Fellowship Award, USA
- 2004–2005 International Doctoral Fellowship, Northwestern University
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Compartmentalized Jet Polymerization as a High-Resolution Process to Continuously Produce Anisometric Microgel Rods with Adjustable Size and Stiffness
A. J. D. Krüger, O. Bakirman, L. P. B. Guerzoni, A. Jans, D. B. Gehlen, D. Rommel, T. Haraszti, A. J. C. Kuehne, L. De Laporte
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https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201903668 | Advanced Materials | 2019 | |
Controlled Covalent Self-Assembly of a Homopolymer for Multiscale Materials Engineering
X. Bai, Q. Sun, H. Cui, L. P. B. Guerzoni, S. Wuttke, F. Kiessling, L. De Laporte, T. Lammers and Y. Shi
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https://doi.org/10.1002/adma.202109701 | Advanced Materials | 2022 | |
Engineering Anisotropic Cell Models: Development of Collagen Hydrogel Scaffolds with Magneto-Responsive Peg Microgels for Tissue Engineering Applications
A. L. Castro, S. Vedaraman, T. Haraszti, M. A. Barbosa, R. M. Gonçalves and L. De Laporte
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https://doi.org/10.1002/admt.202301391 | Advanced Materials Technologies | 2024 | |
Functionalized Microgel Rods Interlinked into Soft Macroporous Structures for 3D Cell Culture
D. Rommel, M. Mork, S. Vedaraman, C. Bastard, L. P. B. Guerzoni, Y. Kittel, R. Vinokur, N. Born, T. Haraszti and L. De Laporte
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https://doi.org/10.1002/advs.202103554 | Advanced Science | 2022 | |
High Macromolecular Crowding in Liposomes from Microfluidics
L. P. B. Guerzoni, A. V. C. de Goes, M. Kalacheva, J. Haduła, M. Mork, L. De Laporte and A. J. Boersma
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https://doi.org/10.1002/advs.202201169 | Advanced Science | 2022 | |
How Does Temporal and Sequential Delivery of Multiple Growth Factors Affect Vascularization inside 3d Hydrogels?
C. Bastard, D. Günther, J. Gerardo-Nava, M. Dewerchin, P. Sprycha, C. Licht, A. Lüken, M. Wessling and L. De Laporte
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https://doi.org/10.1002/adtp.202300091 | Advanced Therapeutics | 2023 | |
High-Affinity RGD-Knottin Peptide as a New Tool for Rapid Evaluation of the Binding Strength of Unlabeled RGD-Peptides to alpha(v)beta(3), alpha(v)beta(5), and alpha(5)beta(1) Integrin Receptors
D. Bernhagen, L. De Laporte and P. Timmerman
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https://www.doi.org/10.1021/acs.analchem.7b00554 | Analytical Chemistry | 2017 | |
Varying the Stiffness and Diffusivity of Rod-Shaped Microgels Independently through Their Molecular Building Blocks
Y. Kittel, L. P. B. Guerzoni, C. Itzin, D. Rommel, M. Mork, C. Bastard, B. Häßel, A. Omidinia-Anarkoli, S. P. Centeno, T. Haraszti, K. Kim, J. Guck, A. J. C. Kuehne and L. De Laporte
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https://doi.org/10.1002/anie.202309779 | Angewandte Chemie International Edition | 2023 | |
Cells Feel the Beat – Temporal Effect of Cyclic Mechanical Actuation on Muscle Cells
Y. Chandorkar, C. Bastard, J. Di Russo, T. Haraszti and L. De Laporte
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https://doi.org/10.1016/j.apmt.2022.101492 | Applied Materials Today | 2022 | |
A Layer-by-Layer Single-Cell Coating Technique To Produce Injectable Beating Mini Heart Tissues via Microfluidics
L. P. B. Guerzoni, Y. Tsukamoto, D. B. Gehlen, D. Rommel, T. Haraszti, M. Akashi, L. De Laporte
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https://doi.org/10.1021/acs.biomac.9b00786 | Biomacromolecules | 2019 | |
Cellulose Nanofibril Hydrogel Tubes as Sacrificial Templates for Freestanding Tubular Cell Constructs
J. G. Torres-Rendon, M. Kopf, D. Gehlen, A. Blaeser, H. Fischer, L. De Laporte and A. Walther
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https://www.doi.org/10.1021/acs.biomac.5b01593 | Biomacromolecules | 2016 | |
Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension
C. Licht, J. C. Rose, A. O. Anarkoli, D. Blondel, M. Roccio, T. Haraszti, D. B. Gehlen, J. A. Hubbell, M. P. Lutolf and L. De Laporte
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https://www.doi.org/10.1021/acs.biomac.9b00891 | Biomacromolecules | 2019 |