Prof. Dr.-Ing. Laura De Laporte
Laura De Laporte develops biohybrid and bioinspired materials for advanced medical applications, for example to replicate the complex structure of natural tissues. To achieve this, she is working on new synthetic material concepts and new methods of manufacture, combining engineering, chemistry and biology to design biomaterials that control and direct the interaction with cells. Her team designs low-invasive, polymeric regenerative hydrogel therapies, consisting of nano –and micron-scale building blocks that orient after injection to repair anisotropic tissues, such as the spinal cord. In addition, dynamic hydrogels are created for drug delivery and to study mechanobiology.
Curriculum Vitae
Laura De Laporte studied chemical engineering at Ghent University (Belgium). She received her PhD from Northwestern University (Evanston, USA) in the group of Prof. Lonnie Shea, where she developed guided implants for nerve regeneration. At EPFL (Lausanne, Switzerland), she researched regenerative hydrogels in the group of Prof. Jeffrey Hubbell. From 2013 to 2018, Laura De Laporte led a junior research group at DWI – Leibniz Institute for Interactive Materials in Aachen and was awarded a Starting Grant from the European Research Council in 2015. In October 2017, she completed her habilitation at the Department of Chemistry of RWTH Aachen University. In 2018, she was one of five excellent female researchers who have received funding from the Leibniz Programme for female Professors and became an associate professor in the Chemistry Department with the teaching and research area Advanced Materials for Biomedicine. Since 2021, she is also part of the Institute for Applied Medical Engineering and affiliated to the University Hospital RWTH Aachen. In 2022, De Laporte received an ERC Consolidator Grant for the "Heartbeat" project.
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Selected professional functions, honors and awards
- Since 2021 Board of International Society of Biofabrication (ISBF)
- 2020-2021 Associated Editor ACS Applied Materials and Interfaces
- Since 2020 Editorial Advisory Board Advanced Healthcare Materials
- 2019 Steinhofer Lecture
- 2018 Young Investigator Award - Engineering Conferences International
- 2016 Max Buchner Research Foundation
- 2008–2009 Terminal Year Richter Fellowship, Northwestern University
- 2008 AIChE Women's Initiatives Committee Travel Award, USA
- 2006-2008 Conference Travel Grant, Northwestern University (annual)
- 2006 CGM Travel Fellowship Award, USA
- 2004–2005 International Doctoral Fellowship, Northwestern University
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Cellular Architects at Work: Cells Building Their Own Microgel Houses
S. Bulut, D. Günther, M. Bund, C. Haats, T. Bissing, C. Bastard, M. Wessling, L. De Laporte and A. Pich
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https://doi.org/10.1002/adhm.202302957 | Advanced Healthcare Materials | 2023 | |
Cells Feel the Beat – Temporal Effect of Cyclic Mechanical Actuation on Muscle Cells
Y. Chandorkar, C. Bastard, J. Di Russo, T. Haraszti and L. De Laporte
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https://doi.org/10.1016/j.apmt.2022.101492 | Applied Materials Today | 2022 | |
Cell Guiding Multicomponent Nanoyarn Tendon Scaffolds with Tunable Morphology and Flexibility
L. Schynkel, M. Meeremans, A. A. Meyer, E. Schoolaert, J. Geltmeyer, A. Omidinia-Anarkoli, S. Van Vlierberghe, L. Daelemans, L. De Laporte, C. De Schauwer, R. Hoogenboom and K. De Clerck
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https://doi.org/10.1021/acsami.3c08241 | ACS Applied Materials & Interfaces | 2023 | |
Cell Encapsulation in Soft, Anisometric Poly(ethylene) Glycol Microgels Using a Novel Radical-Free Microfluidic System
L. P. B. Guerzoni, J. C. Rose, D. B. Gehlen, A. Jans, T. Haraszti, M. Wessling, A. J. C. Kuehne and L. De Laporte
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https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201900692 | Small | 2019 | |
Call for Special Issue Papers: Special Issue for Prof. James Kirkpatrick in Honor of His Achievements in Tissue Engineering/Regenerative Medicine
L. De Laporte and J. van den Beucken
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https://doi.org/10.1089/ten.tea.2023.29050.cfp | Tissue Eng Part A | 2023 | |
Biofunctionalized aligned microgels provide 3D cell guidance to mimic complex tissue matrices
J. C. Rose, D. B. Gehlen, T. H. J. Kohler, C. J. Licht and L. De Laporte
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https://www.doi.org/10.1016/j.biomaterials.2018.02.001 | Biomaterials | 2018 | |
Bioactive gyroid scaffolds formed by sacrificial templating of nanocellulose and nanochitin hydrogels as instructive platforms for biomimetic tissue engineering
J. G. Torres-Rendon, T. Femmer, L. De Laporte, T. Tigges, K. Rahimi, F. Gremse, S. Zafarnia, W. Lederle, S. Ifuku, M. Wessling, J. G. Hardy and A. Walther
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https://www.doi.org/10.1002/adma.201405873 | Adv Mater | 2015 | |
Bicyclic RGD peptides enhance nerve growth in synthetic PEG-based Anisogels
S. Vedaraman, D. Bernhagen, T. Haraszti, C. Licht, A. Castro Nava, A. Omidinia Anarkoli, P. Timmerman and L. De Laporte
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https://doi.org/10.1039/D0BM02051F | Biomaterials Science | 2021 | |
Annealing High Aspect Ratio Microgels into Macroporous 3D Scaffolds Allows for Higher Porosities and Effective Cell Migration
A. C. Suturin, A. J. D. Krüger, K. Neidig, N. Klos, N. Dolfen, M. Bund, T. Gronemann, R. Sebers, A. Manukanc, G. Yazdani, Y. Kittel, D. Rommel, T. Haraszti, J. Köhler and L. De Laporte
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https://doi.org/10.1002/adhm.202200989 | Advanced Healthcare Materials | 2022 | |
Anisometric Microstructures to Determine Minimal Critical Physical Cues Required for Neurite Alignment
S. Vedaraman, A. Perez-Tirado, T. Haraszti, J. Gerardo-Nava, A. Nishiguchi and L. De Laporte
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https://doi.org/10.1002/adhm.202100874 | Advanced Healthcare Materials | 2021 | |
An Injectable Hybrid Hydrogel with Oriented Short Fibers Induces Unidirectional Growth of Functional Nerve Cells
A. Omidinia-Anarkoli, S. Boesveld, U. Tuvshindorj, J. C. Rose, T. Haraszti and L. De Laporte
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https://www.doi.org/10.1002/smll.201702207 | Small | 2017 | |
Actuation of Soft Thermoresponsive Hydrogels Mechanically Stimulates Osteogenesis in Human Mesenchymal Stem Cells without Biochemical Factors
A. Castro Nava, I. C. Doolaar, N. Labude-Weber, H. Malyaran, S. Babu, Y. Chandorkar, J. Di Russo, S. Neuss and L. De Laporte
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https://doi.org/10.1021/acsami.3c11808 | ACS Applied Materials & Interfaces | 2023 |