Prof. Dr.-Ing. Laura De Laporte
Laura De Laporte develops biohybrid and bioinspired materials for advanced medical applications, for example to replicate the complex structure of natural tissues. To achieve this, she is working on new synthetic material concepts and new methods of manufacture, combining engineering, chemistry and biology to design biomaterials that control and direct the interaction with cells. Her team designs low-invasive, polymeric regenerative hydrogel therapies, consisting of nano –and micron-scale building blocks that orient after injection to repair anisotropic tissues, such as the spinal cord. In addition, dynamic hydrogels are created for drug delivery and to study mechanobiology.
Curriculum Vitae
Laura De Laporte studied chemical engineering at Ghent University (Belgium). She received her PhD from Northwestern University (Evanston, USA) in the group of Prof. Lonnie Shea, where she developed guided implants for nerve regeneration. At EPFL (Lausanne, Switzerland), she researched regenerative hydrogels in the group of Prof. Jeffrey Hubbell. From 2013 to 2018, Laura De Laporte led a junior research group at DWI – Leibniz Institute for Interactive Materials in Aachen and was awarded a Starting Grant from the European Research Council in 2015. In October 2017, she completed her habilitation at the Department of Chemistry of RWTH Aachen University. In 2018, she was one of five excellent female researchers who have received funding from the Leibniz Programme for female Professors and became an associate professor in the Chemistry Department with the teaching and research area Advanced Materials for Biomedicine. Since 2021, she is also part of the Institute for Applied Medical Engineering and affiliated to the University Hospital RWTH Aachen. In 2022, De Laporte received an ERC Consolidator Grant for the "Heartbeat" project.
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Selected professional functions, honors and awards
- Since 2021 Board of International Society of Biofabrication (ISBF)
- 2020-2021 Associated Editor ACS Applied Materials and Interfaces
- Since 2020 Editorial Advisory Board Advanced Healthcare Materials
- 2019 Steinhofer Lecture
- 2018 Young Investigator Award - Engineering Conferences International
- 2016 Max Buchner Research Foundation
- 2008–2009 Terminal Year Richter Fellowship, Northwestern University
- 2008 AIChE Women's Initiatives Committee Travel Award, USA
- 2006-2008 Conference Travel Grant, Northwestern University (annual)
- 2006 CGM Travel Fellowship Award, USA
- 2004–2005 International Doctoral Fellowship, Northwestern University
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Translating Therapeutic Microgels into Clinical Applications
Y. Kittel, A. J. C. Kühne and L. De Laporte
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https://doi.org/10.1002/adhm.202101989 | Advanced Healthcare Materials | 2021 | |
Annealing High Aspect Ratio Microgels into Macroporous 3D Scaffolds Allows for Higher Porosities and Effective Cell Migration
A. C. Suturin, A. J. D. Krüger, K. Neidig, N. Klos, N. Dolfen, M. Bund, T. Gronemann, R. Sebers, A. Manukanc, G. Yazdani, Y. Kittel, D. Rommel, T. Haraszti, J. Köhler and L. De Laporte
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https://doi.org/10.1002/adhm.202200989 | Advanced Healthcare Materials | 2022 | |
Cells Feel the Beat – Temporal Effect of Cyclic Mechanical Actuation on Muscle Cells
Y. Chandorkar, C. Bastard, J. Di Russo, T. Haraszti and L. De Laporte
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https://doi.org/10.1016/j.apmt.2022.101492 | Applied Materials Today | 2022 | |
Controlled Covalent Self-Assembly of a Homopolymer for Multiscale Materials Engineering
X. Bai, Q. Sun, H. Cui, L. P. B. Guerzoni, S. Wuttke, F. Kiessling, L. De Laporte, T. Lammers and Y. Shi
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https://doi.org/10.1002/adma.202109701 | Advanced Materials | 2022 | |
ECM-Transmitted Shear Stress Induces Apoptotic Cell Extrusion in Early Breast Gland Development
F. Friedland, S. Babu, R. Springer, J. Konrad, Y. Herfs, S. Gerlach, J. Gehlen, H.-J. Krause, L. De Laporte, R. Merkel and E. Noetzel
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https://doi.org/10.3389/fcell.2022.947430 | Frontiers in Cell and Developmental Biology | 2022 | |
Engineering the Acoustic Response and Drug Loading Capacity of PBCA-Based Polymeric Microbubbles with Surfactants
R. A. Barmin, A. Dasgupta, C. Bastard, L. De Laporte, S. Rütten, M. Weiler, F. Kiessling, T. Lammers and R. M. Pallares
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https://doi.org/10.1021/acs.molpharmaceut.2c00416 | Molecular Pharmaceutics | 2022 | |
Enhanced Stable Cavitation and Nonlinear Acoustic Properties of Poly(Butyl Cyanoacrylate) Polymeric Microbubbles after Bioconjugation
R. A. Barmin, A. Dasgupta, A. Rix, M. Weiler, L. Appold, S. Rütten, F. Padilla, A. J. C. Kuehne, A. Pich, L. De Laporte, F. Kiessling, R. M. Pallares and T. Lammers
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https://doi.org/10.1021/acsbiomaterials.2c01021 | ACS Biomaterials Science & Engineering | 2022 | |
Fabrication of pH-Degradable Supramacromolecular Microgels with Tunable Size and Shape via Droplet-Based Microfluidics
S. H. Jung, S. Bulut, L. P. B. Busca Guerzoni, D. Günther, S. Braun, L. De Laporte and A. Pich
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https://doi.org/10.1016/j.jcis.2022.02.065 | Journal of Colloid and Interface Science | 2022 | |
Functionalized Microgel Rods Interlinked into Soft Macroporous Structures for 3D Cell Culture
D. Rommel, M. Mork, S. Vedaraman, C. Bastard, L. P. B. Guerzoni, Y. Kittel, R. Vinokur, N. Born, T. Haraszti and L. De Laporte
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https://doi.org/10.1002/advs.202103554 | Advanced Science | 2022 | |
High Macromolecular Crowding in Liposomes from Microfluidics
L. P. B. Guerzoni, A. V. C. de Goes, M. Kalacheva, J. Haduła, M. Mork, L. De Laporte and A. J. Boersma
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https://doi.org/10.1002/advs.202201169 | Advanced Science | 2022 | |
How do the Local Physical, Biochemical, and Mechanical Properties of an Injectable Synthetic Anisotropic Hydrogel Affect Oriented Nerve Growth?
S. Babu, I. Chen, S. Vedaraman, J. Gerardo-Nava, C. Licht, Y. Kittel, T. Haraszti, J. Di Russo and L. De Laporte
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https://doi.org/10.1002/adfm.202202468 | Advanced Functional Materials | 2022 | |
Interlinked Macroporous 3d Scaffolds from Microgel Rods
D. Rommel, S. Vedaraman, M. Mork and L. De Laporte
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https://doi.org/10.3791/64010 | Jove-Journal of Visualized Experiments | 2022 |