The Rodriguez-Emmenegger group aims at the development of adaptive biointerfaces and protocells able to interact and direct synthetic and natural systems. Towards this aim, they develop routes to tailor the topology and architecture of synthetic and hybrid macromolecules and program their intermolecular interactions to drive the hierarchical directed self-assembly into interfaces and materials capable to selectively and actively (autonomously) alter their properties to environmental cues —biological and artificial. Furthermore, they investigate, how to achieve superselective interfaces by balancing repellency in aqueous systems with multivalent and cooperative attractive interactions.
The Rodriguez-Emmenegger group strives for translating their basic research into adaptive hemocompatible coatings, antimicrobial wound dressings and diagnostic tools. They are also developing new concepts for cell membrane mimics and protocellular systems capable of communicating with living cells and directing their behavior by the exploitation of biophysical and biochemical actions.
Prof. Dr. César Rodriguez-Emmenegger
Team
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
---|---|---|---|---|
Improving Hemocompatibility: How Can Smart Surfaces Direct Blood To Fight against Thrombi
F. Obstals, L. Witzdam, M. Garay-Sarmiento, N. Y. Kostina, J. Quandt, R. Rossaint, S. Singh, O. Grottke and C. Rodriguez-Emmenegger
|
https://doi.org/10.1021/acsami.1c01079 | ACS Applied Materials & Interfaces | 2021 | |
Direct Visualization of Vesicle Disassembly and Reassembly Using Photocleavable Dendrimers Elucidates Cargo Release Mechanisms
S. Li, B. Xia, B. Javed, W. D. Hasley, A. Melendez-Davila, M. Liu, M. Kerzner, S. Agarwal, Q. Xiao, P. Torre, J. G. Bermudez, K. Rahimi, N. Y. Kostina, M. Möller, C. Rodriguez-Emmenegger, M. L. Klein, V. Percec and M. C. Good
|
https://doi.org/10.1021/acsnano.0c02912 | ACS Nano | 2020 | |
Photoinduced Upgrading of Lactic Acid-Based Solvents to Block Copolymer Surfactants
N. Bensabeh, A. Moreno, A. Roig, M. Rahimzadeh, K. Rahimi, J. C. Ronda, V. Cádiz, M. Galià, V. Percec, C. Rodriguez-Emmenegger and G. Lligadas
|
https://doi.org/10.1021/acssuschemeng.9b06599 | ACS Sustainable Chemistry & Engineering | 2019 | |
Kill&Repel Coatings: The Marriage of Antifouling and Bactericidal Properties to Mitigate and Treat Wound Infections
M. Garay-Sarmiento, L. Witzdam, M. Vorobii, C. Simons, N. Herrmann, A. de los Santos Pereira, E. Heine, I. El-Awaad, R. Lütticken, F. Jakob, U. Schwaneberg and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/adfm.202106656 | Advanced Functional Materials | 2021 | |
Dendrimersome Synthetic Cells Harbor Cell Division Machinery of Bacteria
A. M. Wagner, H. Eto, A. Joseph, S. Kohyama, T. Haraszti, R. A. Zamora, M. Vorobii, M. I. Giannotti, P. Schwille and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/adma.202202364 | Advanced Materials | 2022 | |
Zwitterionic Dendrimersomes: A Closer Xenobiotic Mimic of Cell Membranes
A. Joseph, A. M. Wagner, M. Garay-Sarmiento, M. Aleksanyan, T. Haraszti, D. Söder, V. N. Georgiev, R. Dimova, V. Percec and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/adma.202206288 | Advanced Materials | 2022 | |
Biointerfaces and Biopolymers
C. Rodriguez-Emmenegger and H. Zuilhof
|
https://doi.org/10.1002/admi.202202252 | Advanced Materials Interfaces | 2022 | |
Evaluation of Dibenzocyclooctyne and Bicyclononyne Click Reaction on Azido-Functionalized Antifouling Polymer Brushes Via Microspotting
B. Yang, Y. Wang, M. Vorobii, E. Sauter, M. Koenig, R. Kumar, C. Rodriguez-Emmenegger and M. Hirtz
|
https://doi.org/10.1002/admi.202102325 | Advanced Materials Interfaces | 2022 | |
Interactive Hemocompatible Nanocoating to Prevent Surface-Induced Coagulation in Medical Devices
J. Quandt, M. Garay-Sarmiento, L. Witzdam, J. Englert, Y. Rutsch, C. Stöcker, F. Obstals, O. Grottke and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/admi.202201055 | Advanced Materials Interfaces | 2022 | |
Controlled Surface Adhesion of Macrophages via Patterned Antifouling Polymer Brushes
M. Vorobii, C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/anbr.202000029 | Advanced NanoBiomed Research | 2020 | |
Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life
A. M. Wagner, J. Quandt, D. Söder, M. Garay-Sarmiento, A. Joseph, V. S. Petrovskii, L. Witzdam, T. Hammoor, P. Steitz, T. Haraszti, I. I. Potemkin, N. Y. Kostina, A. Herrmann and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/advs.202200617 | Advanced Science | 2022 | |
Enhanced Concanavalin A Binding to Preorganized Mannose Nanoarrays in Glycodendrimersomes Revealed Multivalent Interactions
N. Yu. Kostina, D. Söder, T. Haraszti, Q. Xiao, K. Rahimi, B. E. Partridge, M. L. Klein, V. Percec and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/anie.202100400 | Angewandte Chemie International Edition | 2021 |