PhD student
Lena Witzdam, M.Sc.
Lena Witzdam works on the development of adaptive hemocompatible coatings for medical applications. The coatings are engineered to passively prevent thrombus formation by modification with polymer brushes but are also able to communicate with blood and direct it in a self-regulated manner. The inspiration for this is nature and the mechanisms used by the body to achieve a balance between clotting and fibrinolysis.
Lena Witzdam is part of the RG Rodriguez-Emmenegger.
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Enhancing Hemocompatibility in Ecmo Systems with a Fibrinolytic Interactive Coating: In Vitro Evaluation of Blood Clot Lysis Using a 3d Microfluidic Model
L. Witzdam, S. Sandhu, S. Shin, Y. Hong, S. Kamal, O. Grottke, K. E. Cook and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/mabi.202400530 | Macromolecular Bioscience | 2025 | |
|
Steps toward Recapitulating Endothelium: A Perspective on the Next Generation of Hemocompatible Coatings
L. Witzdam, T. White and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/mabi.202400152 | Macromolecular Bioscience | 2024 | |
|
Brush-Like Coatings Provide a Cloak of Invisibility to Titanium Implants
L. Witzdam, M. Garay-Sarmiento, M. Gagliardi, Y. L. Meurer, Y. Rutsch, J. Englert, S. Philipsen, A. Janem, R. Alsheghri, F. Jakob, D. G. M. Molin, U. Schwaneberg, N. M. S. van den Akker and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/mabi.202300434 | Macromolecular Bioscience | 2023 | |
|
Green Solvent-Based Antifouling Polymer Brushes Demonstrate Excellent Hemocompatibility
J. Englert, M. Palà, L. Witzdam, F. Rayatdoost, O. Grottke, G. Lligadas and C. Rodriguez-Emmenegger
|
https://doi.org/10.1021/acs.langmuir.3c02765 | Langmuir | 2023 | |
|
Synthetic Evolution of a Supramolecular Harpooning Mechanism to Immobilize Vesicles at Antifouling Interfaces
J. Englert, L. Witzdam, D. Söder, M. Garay-Sarmiento, A. Joseph, A. M. Wagner and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/macp.202300306 | Macromolecular Chemistry and Physics | 2023 | |
|
Tackling the Root Cause of Surface-Induced Coagulation: Inhibition of Fxii Activation to Mitigate Coagulation Propagation and Prevent Clotting
L. Witzdam, B. Vosberg, K. Große-Berkenbusch, S. Stoppelkamp, H. P. Wendel and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202300321 | Macromolecular Bioscience | 2023 | |
|
Brush-Like Interface on Surface-Attached Hydrogels Repels Proteins and Bacteria
L. Witzdam, Y. L. Meurer, M. Garay-Sarmiento, M. Vorobii, D. Söder, J. Quandt, T. Haraszti and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/mabi.202200025 | Macromolecular Bioscience | 2022 | |
|
Interactive Hemocompatible Nanocoating to Prevent Surface-Induced Coagulation in Medical Devices
J. Quandt, M. Garay-Sarmiento, L. Witzdam, J. Englert, Y. Rutsch, C. Stöcker, F. Obstals, O. Grottke and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/admi.202201055 | Advanced Materials Interfaces | 2022 | |
|
Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life
A. M. Wagner, J. Quandt, D. Söder, M. Garay-Sarmiento, A. Joseph, V. S. Petrovskii, L. Witzdam, T. Hammoor, P. Steitz, T. Haraszti, I. I. Potemkin, N. Y. Kostina, A. Herrmann and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/advs.202200617 | Advanced Science | 2022 | |
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Improving Hemocompatibility: How Can Smart Surfaces Direct Blood To Fight against Thrombi
F. Obstals, L. Witzdam, M. Garay-Sarmiento, N. Y. Kostina, J. Quandt, R. Rossaint, S. Singh, O. Grottke and C. Rodriguez-Emmenegger
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https://doi.org/10.1021/acsami.1c01079 | ACS Applied Materials & Interfaces | 2021 | |
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Kill&Repel Coatings: The Marriage of Antifouling and Bactericidal Properties to Mitigate and Treat Wound Infections
M. Garay-Sarmiento, L. Witzdam, M. Vorobii, C. Simons, N. Herrmann, A. de los Santos Pereira, E. Heine, I. El-Awaad, R. Lütticken, F. Jakob, U. Schwaneberg and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/adfm.202106656 | Advanced Functional Materials | 2021 |