The Rodriguez-Emmenegger group aims at the development of adaptive biointerfaces and protocells able to interact and direct synthetic and natural systems. Towards this aim, they develop routes to tailor the topology and architecture of synthetic and hybrid macromolecules and program their intermolecular interactions to drive the hierarchical directed self-assembly into interfaces and materials capable to selectively and actively (autonomously) alter their properties to environmental cues —biological and artificial. Furthermore, they investigate, how to achieve superselective interfaces by balancing repellency in aqueous systems with multivalent and cooperative attractive interactions.
The Rodriguez-Emmenegger group strives for translating their basic research into adaptive hemocompatible coatings, antimicrobial wound dressings and diagnostic tools. They are also developing new concepts for cell membrane mimics and protocellular systems capable of communicating with living cells and directing their behavior by the exploitation of biophysical and biochemical actions.
Prof. Dr. César Rodriguez-Emmenegger
Team
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Brush-Like Coatings Provide a Cloak of Invisibility to Titanium Implants
L. Witzdam, M. Garay-Sarmiento, M. Gagliardi, Y. L. Meurer, Y. Rutsch, J. Englert, S. Philipsen, A. Janem, R. Alsheghri, F. Jakob, D. G. M. Molin, U. Schwaneberg, N. M. S. van den Akker and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202300434 | Macromolecular Bioscience | 2023 | |
Glycan-Driven Formation of Raft-Like Domains with Hierarchical Periodic Nanoarrays on Dendrimersome Synthetic Cells
A. M. Wagner, N. Y. Kostina, Q. Xiao, M. L. Klein, V. Percec and C. Rodriguez-Emmenegger
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https://doi.org/10.1021/acs.biomac.3c01027 | Biomacromolecules | 2023 | |
Green Solvent-Based Antifouling Polymer Brushes Demonstrate Excellent Hemocompatibility
J. Englert, M. Palà, L. Witzdam, F. Rayatdoost, O. Grottke, G. Lligadas and C. Rodriguez-Emmenegger
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https://doi.org/10.1021/acs.langmuir.3c02765 | Langmuir | 2023 | |
Self-Assembly of Glycerol-Amphiphilic Janus Dendrimers Amplifies and Indicates Principles for the Selection of Stereochemistry by Biological Membranes
D. Zhang, Q. Xiao, M. Rahimzadeh, M. Liu, C. Rodriguez-Emmenegger, Y. Miyazaki, W. Shinoda and V. Percec
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https://doi.org/10.1021/jacs.3c00389 | Journal of the American Chemical Society | 2023 | |
Synthetic Evolution of a Supramolecular Harpooning Mechanism to Immobilize Vesicles at Antifouling Interfaces
J. Englert, L. Witzdam, D. Söder, M. Garay-Sarmiento, A. Joseph, A. M. Wagner and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/macp.202300306 | Macromolecular Chemistry and Physics | 2023 | |
Tackling the Root Cause of Surface-Induced Coagulation: Inhibition of Fxii Activation to Mitigate Coagulation Propagation and Prevent Clotting
L. Witzdam, B. Vosberg, K. Große-Berkenbusch, S. Stoppelkamp, H. P. Wendel and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202300321 | Macromolecular Bioscience | 2023 | |
A Green Solvent-to-Polymer Upgrading Approach to Water-Soluble LCST Poly(N-Substituted Lactamide Acrylate)s
M. Palà, H. El Khannaji, M. Garay-Sarmiento, J. C. Ronda, V. Cádiz, M. Galià, V. Percec, C. Rodriguez-Emmenegger and G. Lligadas
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https://doi.org/10.1039/D2GC02780A | Green Chemistry | 2022 | |
Biointerfaces and Biopolymers
C. Rodriguez-Emmenegger and H. Zuilhof
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https://doi.org/10.1002/admi.202202252 | Advanced Materials Interfaces | 2022 | |
Brush-Like Interface on Surface-Attached Hydrogels Repels Proteins and Bacteria
L. Witzdam, Y. L. Meurer, M. Garay-Sarmiento, M. Vorobii, D. Söder, J. Quandt, T. Haraszti and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202200025 | Macromolecular Bioscience | 2022 | |
Dendrimersome Synthetic Cells Harbor Cell Division Machinery of Bacteria
A. M. Wagner, H. Eto, A. Joseph, S. Kohyama, T. Haraszti, R. A. Zamora, M. Vorobii, M. I. Giannotti, P. Schwille and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/adma.202202364 | Advanced Materials | 2022 | |
Evaluation of Dibenzocyclooctyne and Bicyclononyne Click Reaction on Azido-Functionalized Antifouling Polymer Brushes Via Microspotting
B. Yang, Y. Wang, M. Vorobii, E. Sauter, M. Koenig, R. Kumar, C. Rodriguez-Emmenegger and M. Hirtz
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https://doi.org/10.1002/admi.202102325 | Advanced Materials Interfaces | 2022 | |
Globular Hydrophilic Poly(acrylate)s by an Arborescent Grafting-from Synthesis
J. Robin Höhner, Rustam A. Gumerov, Igor I. Potemkin, César Rodriguez-Emmenegger, Nina Yu. Kostina, Ahmed Mourran, Jenny Englert, David Schröter, Lennart Janke, and Martin Möller
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https://doi.org/10.1021/acs.macromol.1c02548 | Macromolecules | 2022 |