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Research Group Schwaneberg

Molecular Biotechnology & Protein Engineering
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The expertise of the Schwaneberg group lies in protein engineering by directed evolution and rational design. Directed evolution methodologies were awarded with the Nobel Prize in chemistry in 2018 and workgroup Schwaneberg is ranked 3rd in respect to published manuscripts (Web of Science; search term “directed evolution”). Research is organized in 5 divisions with the general goal to advance directed evolution methodologies, to discover fundamental design principles of proteins, and to perform translational research within the areas of interactive materials (focus on plant health, medicine), biocatalysis, and circular bioeconomy. Developed protein engineering strategies such as KnowVolution are used to combine computational and experimental efforts and thereby to ensure efficient protein design with minimal experimental efforts and a molecular understanding of improved properties.

Member of the Scientific Board

Prof. Dr. Ulrich Schwaneberg

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  • PhD student

    Ahmed Hegazy, M.Sc.

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    Hegazy
  • Science Support Team

    Christian Simons, M.Sc.

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    Simons
  • Postdoc

    Deniz Thiel

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    B0.57 / B-1.51
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  • Postdoc

    Dr. Amanda Staudt

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  • Postdoc

    Dr. Florian Bourdeaux

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  • Dr. Nikola Mijailovic

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  • Project Leader

    Dr. Patrick J. Bakkes

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  • Postdoc

    Jan Gebauer

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    Jan Gebauer
  • Science Support Team

    Jens Gruber

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  • PhD student

    Julian Karl

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    Julian Karl
  • Science Support Team

    Michael Eßer

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    Eßer
  • PhD student

    Niklas Herrmann, M.Sc.

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    Herrmann
  • Project

    EcoGuard

    Rainproof delivery systems to protect vine against vine peronospora and cherry vinegar fly (2818OE039)
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  • Project

    PEBIOTE

    PEPBIOTE Anchor Peptide as a green and versatile stategies for applicateion of BIObased additives in coating of Textiles
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  • Project

    ProSeed

    Mikroplastik freie Saatgutbehandlung
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  • Project

    BioCoat

    BioTexFuture - Bio-based coatings for bio-based fibres in high-performance textiles
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  • Project

    Ankerpeptide

    Eine grüne und vielseitige Strategie für die Applikation von BIObasierten Additiven in Textil- und Kunststoffbeschichtungen
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  • Project

    Anchor peptides that bind to hair

    Identification of anchor peptides that can specifically bind to the surface of hair without simultaneously binding to skin cells
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  • Project

    In FuProts

    Rainfasten Insecticidal Fusion Proteins for Plant Protection
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  • Project

    Bio4MatPro

    Competence Center for the Biological Transformation of Materials Science and Production Engineering
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  • Project

    PleuraPlug

    Surface functionalized bio-based and injectable patches for tissue regeneration for traumatic pleural injuries
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  • Project

    GreenProtect

    A Sustainable Release System to Produce More Healthy Food with Less Pesticide
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  • Project

    KlarTEXt

    Cooperation platform to dynamise a sustainable and transformative textile economy
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  • Project

    Heart2.0

    Development of an active interface system for the interior of artificial hearts and heart support systems
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  • Publication

    Grafting PNIPAAm from beta-barrel shaped transmembrane nanopores

    H. Charan, J. Kinzel, U. Glebe, D. Anand, T. M. Garakani, L. L. Zhu, M. Bocola, U. Schwaneberg and A. Boker
    Biomaterials Vol. 107 115-123 (2016)
    https://www.doi.org/10.1016/j.biomaterials.2016.08.033
  • Publication

    Photophysics of the LOV-Based Fluorescent Protein Variant iLOV-Q489K Determined by Simulation and Experiment

    M. D. Davari, B. Kopka, M. Wingen, M. Bocola, T. Drepper, K. E. Jaeger, U. Schwaneberg and U. Krauss
    Journal of Physical Chemistry B Vol. 120 (13) 3344-3352 (2016)
    https://www.doi.org/10.1021/acs.jpcb.6b01512
  • Publication

    What's My Substrate? Computational Function Assignment of Candida parapsilosis ADH5 by Genome Database Search, Virtual Screening, and QM/MM Calculations

    G. V. Dhoke, Y. Ensari, M. D. Davari, A. J. Ruff, U. Schwaneberg and M. Bocola
    Journal of Chemical Information and Modeling Vol. 56 (7) 1313-1323 (2016)
    https://www.doi.org/10.1021/acs.jcim.6b00076
  • Publication

    CaLB Catalyzed Conversion of epsilon-Caprolactone in Aqueous Medium. Part 1: Immobilization of CaLB to Microgels

    S. Engel, H. Hock, M. Bocola, H. Keul, U. Schwaneberg and M. Moller
    Polymers Vol. 8 (10) (2016)
    https://www.doi.org/10.3390/polym8100372
  • Publication

    A whole cell biocatalyst for double oxidation of cyclooctane

    C. A. Muller, A. M. Weingartner, A. Dennig, A. J. Ruff, H. Groger and U. Schwaneberg
    Journal of Industrial Microbiology & Biotechnology Vol. 43 (12) 1641-1646 (2016)
    https://www.doi.org/10.1007/s10295-016-1844-5
  • Publication

    Reactive Copolymers Based on N-Vinyl Lactams with Pyridyl Disulfide Side Groups via RAFT Polymerization and Postmodification via Thiol-Disulfide Exchange Reaction

    H. Peng, K. Rubsam, X. B. Huang, F. Jakob, M. Karperien, U. Schwaneberg and A. Pich
    Macromolecules Vol. 49 (19) 7141-7154 (2016)
    https://www.doi.org/10.1021/acs.macromol.6b01210
  • Publication

    Reversible Deactivation of Enzymes by Redox-Responsive Nanogel Carriers

    H. Peng, K. Rubsam, F. Jakob, P. Pazdzior, U. Schwaneberg and A. Pich
    Macromolecular Rapid Communications Vol. 37 (21) 1765-1771 (2016)
    https://www.doi.org/10.1002/marc.201600476
  • Publication

    Tunable Enzymatic Activity and Enhanced Stability of Cellulase Immobilized in Biohybrid Nanogels

    H. Peng, K. Rubsam, F. Jakob, U. Schwaneberg and A. Pich
    Biomacromolecules Vol. 17 (11) 3619-3631 (2016)
    https://www.doi.org/10.1021/acs.biomac.6b01119
  • Publication

    Screening through the PLICable promoter toolbox enhances protein production in Escherichia coli

    J. H. Yang, A. J. Ruff, S. N. Hamer, F. Cheng and U. Schwaneberg
    Biotechnology Journal Vol. 11 (12) 1639-1647 (2016)
    https://www.doi.org/10.1002/biot.201600270
  • Publication

    Directed evolution of P450cin for mediated electron transfer

    K. D. Belsare, T. Horn, A. J. Ruff, R. Martinez, A. Magnusson, D. Holtmann, J. Schrader and U. Schwaneberg
    Protein Engineering Design & Selection Vol. 30 (2) 119-127 (2017)
    https://www.doi.org/10.1093/protein/gzw072
  • Publication

    Sugar-Improved Enzymatic Synthesis of Biodiesel with Yarrowia lipolytica Lipase 2

    H. Cao, M. Wang, L. Deng, L. Liu, U. Schwaneberg, T. W. Tan, F. Wang and K. L. Nie
    Energy & Fuels Vol. 31 (6) 6248-6256 (2017)
    https://www.doi.org/10.1021/acs.energyfuels.7b01091
  • Publication

    Nano-thin walled micro-compartments from transmembrane protein-polymer conjugates

    H. Charan, U. Glebe, D. Anand, J. Kinzel, L. L. Zhu, M. Bocola, T. M. Garakani, U. Schwaneberg and A. Boker
    Soft Matter Vol. 13 (15) 2866-2875 (2017)
    https://www.doi.org/10.1039/c6sm02520j
  • Publication

    An Enzymatic Route to alpha-Tocopherol Synthons: Aromatic Hydroxylation of Pseudocumene and Mesitylene with P450 BM3

    A. Dennig, A. M. Weingartner, T. Kardashliev, C. A. Muller, E. Tassano, M. Schurmann, A. J. Ruff and U. Schwaneberg
    Chemistry-a European Journal Vol. 23 (71) 17981-17991 (2017)
    https://www.doi.org/10.1002/chem.201703647
  • Publication

    Inversion of cpADH5 Enantiopreference and Altered Chain Length Specificity for Methyl 3-Hydroxyalkanoates

    Y. Ensari, G. V. Dhoke, M. D. Davari, M. Bocola, A. J. Ruff and U. Schwaneberg
    Chemistry-a European Journal Vol. 23 (51) 12636-12645 (2017)
    https://www.doi.org/10.1002/chem.201702581
  • Publication

    Sortase-Mediated Surface Functionalization of Stimuli-Responsive Microgels

    E. Gau, D. M. Mate, Z. Zou, A. Oppermann, A. Topel, F. Jakob, D. Woll, U. Schwaneberg and A. Pich
    Biomacromolecules Vol. 18 (9) 2789-2798 (2017)
    https://www.doi.org/10.1021/acs.biomac.7b00720
  • Publication

    2-Methyl-2,4-pentanediol (MPD) boosts as detergent-substitute the performance of beta-barrel hybrid catalyst for phenylacetylene polymerization

    J. Kinzel, D. F. Sauer, M. Bocola, M. Arlt, T. M. Garakani, A. Thiel, K. Beckerle, T. Polen, J. Okuda and U. Schwaneberg
    Beilstein Journal of Organic Chemistry Vol. 13 1498-1506 (2017)
    https://www.doi.org/10.3762/bjoc.13.148
  • Publication

    Electron transfer pathways in a light, oxygen, voltage (LOV) protein devoid of the photoactive cysteine

    B. Kopka, K. Magerl, A. Savitsky, M. D. Davari, K. Rollen, M. Bocola, B. Dick, U. Schwaneberg, K. E. Jaeger and U. Krauss
    Scientific Reports Vol. 7 (2017)
    https://www.doi.org/10.1038/s41598-017-13420-1
  • Publication

    Engineering Enhanced Pore Sizes Using FhuA Delta 1-160 from E. coli Outer Membrane as Template

    Z. Z. Liu, I. Ghai, M. Winterhalter and U. Schwaneberg
    Acs Sensors Vol. 2 (11) 1619-1626 (2017)
    https://www.doi.org/10.1021/acssensors.7b00481
  • Publication

    Are Directed Evolution Approaches Efficient in Exploring Nature's Potential to Stabilize a Lipase in Organic Cosolvents?

    U. Markel, L. L. Zhu, V. J. Frauenkron-Machedjou, J. Zhao, M. Bocola, M. D. Davari, K. E. Jaeger and U. Schwaneberg
    Catalysts Vol. 7 (5) (2017)
    https://www.doi.org/10.3390/catal7050142
  • Publication

    Biofunctional Microgel-Based Fertilizers for Controlled Foliar Delivery of Nutrients to Plants

    R. A. Meurer, S. Kemper, S. Knopp, T. Eichert, F. Jakob, H. E. Goldbach, U. Schwaneberg and A. Pich
    Angewandte Chemie-International Edition Vol. 56 (26) 7380-7386 (2017)
    https://www.doi.org/10.1002/anie.201701620
  • Publication

    Anchor peptides: A green and versatile method for polypropylene functionalization

    K. Rubsam, B. Stomps, A. Boker, F. Jakob and U. Schwaneberg
    Polymer Vol. 116 124-132 (2017)
    https://www.doi.org/10.1016/j.polymer.2017.03.070
  • Publication

    Casting epPCR (cepPCR): A Simple Random Mutagenesis Method to Generate High Quality Mutant Libraries

    J. H. Yang, A. J. Ruff, M. Arlt and U. Schwaneberg
    Biotechnology and Bioengineering Vol. 114 (9) 1921-1927 (2017)
    https://www.doi.org/10.1002/bit.26327
  • Publication

    Sortase-Mediated Ligation of Purely Artificial Building Blocks

    X. L. Dai, D. M. Mate, U. Glebe, T. M. Garakani, A. Korner, U. Schwaneberg and A. Boker
    Polymers Vol. 10 (2) (2018)
    https://www.doi.org/10.3390/polym10020151
  • Publication

    A Comparative Reengineering Study of cpADH5 through Iterative and Simultaneous Multisite Saturation Mutagenesis

    Y. Ensari, G. V. Dhoke, M. D. Davari, A. J. Ruff and U. Schwaneberg
    Chembiochem Vol. 19 (14) 1563-1569 (2018)
    https://www.doi.org/10.1002/cbic.201800159
  • Publication

    Theoretical Model of the Protochlorophyllide Oxidoreductase from a Hierarchy of Protocols

    S. Gholami, A. Nenov, I. Rivalta, M. Bocola, A. K. Bordbar, U. Schwaneberg, M. D. Davari and M. Garavelli
    Journal of Physical Chemistry B Vol. 122 (31) 7668-7681 (2018)
    https://www.doi.org/10.1021/acs.jpcb.8b04231
  • Publication

    Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis

    A. R. Grimm, D. F. Sauer, M. D. Davari, L. L. Zhu, M. Bocola, S. Kato, A. Onoda, T. Hayashi, J. Okuda and U. Schwaneberg
    Acs Catalysis Vol. 8 (4) 3358-3364 (2018)
    https://www.doi.org/10.1021/acscatal.7b03652
  • Publication

    A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium-Nitrobindin Metalloprotein

    A. R. Grimm, D. F. Sauer, T. Polen, L. L. Zhu, T. Hayashi, J. Okuda and U. Schwaneberg
    Acs Catalysis Vol. 8 (3) 2611-2614 (2018)
    https://www.doi.org/10.1021/acscatal.7b04369
  • Publication

    Comparison of Candida antarctica Lipase B Variants for Conversion of epsilon-Caprolactone in Aqueous MediumPart 2

    H. Hock, S. Engel, S. Weingarten, H. Keul, U. Schwaneberg, M. Moller and M. Bocola
    Polymers Vol. 10 (5) (2018)
    https://www.doi.org/10.3390/polym10050524
  • Publication

    KnowVolution Campaign of an Aryl Sulfotransferase Increases Activity toward Cellobiose

    S. Islam, D. Laaf, B. Infanzon, H. Pelantova, M. D. Davari, F. Jakob, V. Kren, L. Elling and U. Schwaneberg
    Chemistry-a European Journal Vol. 24 (64) 17117-17124 (2018)
    https://www.doi.org/10.1002/chem.201803729
  • Publication

    A robust protocol for directed aryl sulfotransferase evolution toward the carbohydrate building block GlcNAc

    S. Islam, D. M. Mate, R. Martinez, F. Jakob and U. Schwaneberg
    Biotechnology and Bioengineering Vol. 115 (5) 1106-1115 (2018)
    https://www.doi.org/10.1002/bit.26535
  • Publication

    Directed OmniChange Evolution Converts P450 BM3 into an Alkyltrimethylammonium Hydroxylase

    Y. Ji, A. M. Mertens, C. Gertler, S. Fekiri, M. Keser, D. F. Sauer, K. E. C. Smith and U. Schwaneberg
    Chemistry-a European Journal Vol. 24 (63) 16865-16872 (2018)
    https://www.doi.org/10.1002/chem.201803806
  • Publication

    Directed evolution of an acid Yersinia mollaretii phytase for broadened activity at neutral pH

    G. Korfer, C. Novoa, J. Kern, E. Balla, C. Grutering, M. D. Davari, R. Martinez, L. Vojcic and U. Schwaneberg
    Applied Microbiology and Biotechnology Vol. 102 (22) 9607-9620 (2018)
    https://www.doi.org/10.1007/s00253-018-9308-7
  • Publication

    Directed Evolution of Hyaluronic Acid Synthase from Pasteurella multocida towards High-Molecular-Weight Hyaluronic Acid

    J. Mandawe, B. Infanzon, A. Eisele, H. Zaun, J. Kuballa, M. D. Davari, F. Jakob, L. Elling and U. Schwaneberg
    Chembiochem Vol. 19 (13) 1414-1423 (2018)
    https://www.doi.org/10.1002/cbic.201800093
  • Publication

    Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase

    S. Panneerselvam, A. Shehzad, J. Mueller-Dieckmann, M. Wilmanns, M. Bocola, M. D. Davari and U. Schwaneberg
    Biochimica Et Biophysica Acta-Proteins and Proteomics Vol. 1866 (1) 134-140 (2018)
    https://www.doi.org/10.1016/j.bbapap.2017.07.010
  • Publication

    KnowVolution of the Polymer-Binding Peptide LCI for Improved Polypropylene Binding

    K. Rubsam, M. D. Davari, F. Jakob and U. Schwaneberg
    Polymers Vol. 10 (4) (2018)
    https://www.doi.org/10.3390/polym10040423
  • Publication

    Directed evolution of polypropylene and polystyrene binding peptides

    K. Rubsam, L. Weber, F. Jakob and U. Schwaneberg
    Biotechnology and Bioengineering Vol. 115 (2) 321-330 (2018)
    https://www.doi.org/10.1002/bit.26481
  • Publication

    Enzyme-Polyelectrolyte Complexes Boost the Catalytic Performance of Enzymes

    M. J. Thiele, M. D. Davari, M. Konig, I. Hofmann, N. O. Junker, T. M. Garakani, L. Vojcic, J. Fitter and U. Schwaneberg
    Acs Catalysis Vol. 8 (11) 10876-10887 (2018)
    https://www.doi.org/10.1021/acscatal.8b02935
  • Publication

    A loop engineering strategy improves laccase lcc2 activity in ionic liquid and aqueous solution

    A. M. Wallraf, H. F. Liu, L. L. Zhu, G. Khalfallah, C. Simons, H. Alibiglou, M. D. Davari and U. Schwaneberg
    Green Chemistry Vol. 20 (12) 2801-2812 (2018)
    https://www.doi.org/10.1039/c7gc03776g
  • Publication

    A hydroquinone-specific screening system for directed P450 evolution

    A. M. Weingartner, D. F. Sauer, G. V. Dhoke, M. D. Davari, A. J. Ruff and U. Schwaneberg
    Applied Microbiology and Biotechnology Vol. 102 (22) 9657-9667 (2018)
    https://www.doi.org/10.1007/s00253-018-9328-3
  • Publication

    Unraveling the effects of amino acid substitutions enhancing lipase resistance to an ionic liquid: a molecular dynamics study

    J. Zhao, V. J. Frauenkron-Machedjou, A. Fulton, L. L. Zhu, M. D. Davari, K. E. Jaeger, U. Schwaneberg and M. Bocola
    Physical Chemistry Chemical Physics Vol. 20 (14) 9600-9609 (2018)
    https://www.doi.org/10.1039/c7cp08470f
  • Publication

    Directed sortase A evolution for efficient site-specific bioconjugations in organic co-solvents

    Z. Zou, H. Alibiglou, D. M. Mate, M. D. Davari, F. Jakob and U. Schwaneberg
    Chemical Communications Vol. 54 (81) 11467-11470 (2018)
    https://www.doi.org/10.1039/c8cc06017g
  • Publication

    Sortase-Mediated High-Throughput Screening Platform for Directed Enzyme Evolution

    Z. Zou, D. M. Mate, K. Rubsam, F. Jakob and U. Schwaneberg
    Acs Combinatorial Science Vol. 20 (4) 203-211 (2018)
    https://www.doi.org/10.1021/acscombsci.7b00153
  • Publication

    Directed Evolution Empowered Redesign of Natural Proteins for the Sustainable Production of Chemicals and Pharmaceuticals

    U. T. Bornscheuer, B. Hauer, K. E. Jaeger and U. Schwaneberg
    Angewandte Chemie-International Edition Vol. 58 (1) 36-40 (2019)
    https://www.doi.org/10.1002/anie.201812717
  • Publication

    Anchor Peptide-Mediated Surface Immobilization of a Grubbs-Hoveyda-Type Catalyst for Ring-Opening Metathesis Polymerization

    A. R. S. Grimm, D. F.; Garakani, T. M.; Rubsam, K.; Polen, T.; Davari, M. D.; Jakob, F.; Schiffels, J.; Okuda, J.; Schwaneberg, U.
    Bioconjugate Chemistry Vol. 30 (3) 714-720 (2019)
    https://www.doi.org/10.1021/acs.bioconjchem.8b00874
  • Publication

    Targeting microplastic particles in the void of diluted suspensions

    Islam, S., Apitius, L., Jakob, F., Schwaneberg, U.
    Environment International Vol. 123 428-435 (2019)
    https://www.doi.org/10.1016/j.envint.2018.12.029
  • Publication

    Towards the Evolution of Artificial Metalloenzymes-A Protein Engineer's Perspective

    U. S. Markel, D. F.; Schiffels, J.; Okuda, J.; Schwaneberg, U.
    Angewandte Chemie-International Edition Vol. 58 (14) 4454-4464 (2019)
    https://www.doi.org/10.1002/anie.201811042
  • Publication

    Stimuli-Responsive Poly(N-Vinyllactams) with Glycidyl Side Groups: Synthesis, Characterization, and Conjugation with Enzymes

    H. Peng, K. Rubsam, C. Hu, F. Jakob, U. Schwaneberg and A. Pich
    Biomacromolecules Vol. 20 (2) 992-1006 (2019)
    https://www.doi.org/10.1021/acs.biomac.8b01608
  • Publication

    Biohybrid catalysts for sequential one-pot reactions based on an engineered transmembrane protein

    D. F. Q. Sauer, Y.; Mertens, M. A. S.; Schiffels, J.; Polen, T.; Schwaneberg, U.; Okuda, J.
    Catalysis Science & Technology Vol. 9 (4) 942-946 (2019)
    https://www.doi.org/10.1039/c8cy02236d
  • Publication

    Directed Evolution of a Bacterial Laccase (CueO) for Enzymatic Biofuel Cells

    L. L. C. Zhang, H. Y.; Zou, Z.; Garakani, T. M.; Novoa-Henriquez, C.; Jooyeh, B.; Schwaneberg, U.
    Angewandte Chemie-International Edition Vol. 58 (14) 4562-4565 (2019)
    https://www.doi.org/10.1002/anie.201814069
  • Publication

    Enzyme‐Compatible Dynamic Nanoreactors from Electrostatically Bridged Like‐Charged Surfactants and Polyelectrolytes

    M. J. Thiele, M. D. Davari, I. Hofmann, M. König, C. G. Lopez, L. Vojcic, W. Richtering, U. Schwaneberg and L. A. Tsarkova
    Angewandte Chemie-International Edition Vol. 57 (30) 9402-9407 (2018)
    https://doi.org/10.1002/anie.201805021
  • Publication

    In vitro flow cytometry-based screening platform for cellulase engineering

    G. Korfer, C. Pitzler, L. Vojcic, R. Martinez and U. Schwaneberg
    Sci Rep Vol. 6 26128 (2016)
    https://www.doi.org/10.1038/srep26128
  • Publication

    Chiral separation of D/L-arginine with whole cells through an engineered FhuA nanochannel

    D. Anand, G. V. Dhoke, J. Gehrmann, T. M. Garakani, M. D. Davari, M. Bocola, L. L. Zhua and U. Schwaneberg
    Chemical Communications Vol. 55 (38) 5431-5434 (2019)
    https://doi.org/10.1039/c9cc00154a
  • Publication

    Disulfide Bond Engineering of an Endoglucanase from Penicillium verruculosum to Improve Its Thermostability

    A. Bashirova, S. Pramanik, P. Volkov, A. Rozhkova, V. Nemashkalov, I. Zorov, A. Gusakov, A. Sinitsyn, U. Schwaneberg and M. D. Davari
    International Journal of Molecular Sciences Vol. 20 (7) (2019)
    https://doi.org/10.3390/ijms20071602
  • Publication

    Directed aryl sulfotransferase evolution toward improved sulfation stoichiometry on the example of catechols

    Y. Ji, S. Islam, A. M. Mertens, D. F. Sauer, G. V. Dhoke, F. Jakob and U. Schwaneberg
    Applied Microbiology and Biotechnology Vol. 103 (9) 3761-3771 (2019)
    http://doi.org/10.1007/s00253-019-09688-0
  • Publication

    High Throughput Screening Method for Engineering P450 Towards Terminal Hydroxylation of Fatty Acids

    S. Q. Meng, J. Guo, K. L. Nie, U. Schwaneberg, T. W. Tan, H. J. Xu and L. Liu
    Journal of Biobased Materials and Bioenergy Vol. 13 (1) 79-85 (2019)
    https://doi.org/10.1166/jbmb.2019.1816
  • Publication

    Ternary Complex Formation and Photoactivation of a Photoenzyme Results in Altered Protein Dynamics

    A. M. Stadler, J. Schneidewind, M. Zamponi, E. Knieps-Grunhagen, S. Gholami, U. Schwaneberg, I. Rivalta, M. Garavelli, M. D. Davari, K. E. Jaeger and U. Krauss
    J Phys Chem B (2019)
    https://www.doi.org/10.1021/acs.jpcb.9b06608
  • Publication

    Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles

    G. A. Santos, G. V. Dhoke, M. D. Davari, A. J. Ruff and U. Schwaneberg
    Int J Mol Sci Vol. 20 (13) (2019)
    https://www.doi.org/10.3390/ijms20133353
  • Publication

    KnowVolution of a Fungal Laccase toward Alkaline pH

    C. Novoa, G. V. Dhoke, D. M. Mate, R. Martinez, T. Haarmann, M. Schreiter, J. Eidner, R. Schwerdtfeger, P. Lorenz, M. D. Davari, F. Jakob and U. Schwaneberg
    Chembiochem Vol. 20 (11) 1458-1466 (2019)
    https://www.doi.org/10.1002/cbic.201800807
  • Publication

    A thermostable flavin-based fluorescent protein from Chloroflexus aggregans: a framework for ultra-high resolution structural studies

    V. V. Nazarenko, A. Remeeva, A. Yudenko, K. Kovalev, A. Dubenko, I. M. Goncharov, P. Kuzmichev, A. V. Rogachev, P. Buslaev, V. Borshchevskiy, A. Mishin, G. V. Dhoke, U. Schwaneberg, M. D. Davari, K. E. Jaeger, U. Krauss, V. Gordeliy and I. Gushchin
    Photochem Photobiol Sci Vol. 18 (7) 1793-1805 (2019)
    https://www.doi.org/10.1039/c9pp00067d
  • Publication

    In Situ Monitoring of Membrane Protein Insertion into Block Copolymer Vesicle Membranes and Their Spreading via Potential-Assisted Approach

    T. Mirzaei Garakani, Z. Liu, U. Glebe, J. Gehrmann, J. Lazar, M. A. S. Mertens, M. Moller, N. Hamzelui, L. Zhu, U. Schnakenberg, A. Boker and U. Schwaneberg
    ACS Appl Mater Interfaces Vol. 11 (32) 29276-29289 (2019)
    https://www.doi.org/10.1021/acsami.9b09302
  • Publication

    Membrane-Mimetic Dendrimersomes Engulf Living Bacteria via Endocytosis

    N. Y. Kostina, K. Rahimi, Q. Xiao, T. Haraszti, S. Dedisch, J. P. Spatz, U. Schwaneberg, M. L. Klein, V. Percec, M. Moller and C. Rodriguez-Emmenegger
    Nano Lett Vol. 19 (8) 5732-5738 (2019)
    https://www.doi.org/10.1021/acs.nanolett.9b02349
  • Publication

    Engineered phytases for emerging biotechnological applications beyond animal feeding

    K. R. Herrmann, A. J. Ruff, B. Infanzon and U. Schwaneberg
    Appl Microbiol Biotechnol Vol. 103 (16) 6435-6448 (2019)
    https://www.doi.org/10.1007/s00253-019-09962-1
  • Publication

    Rational surface engineering of an arginine deiminase (an antitumor enzyme) for increased PEGylation efficiency

    F. Cheng, J. Yang, U. Schwaneberg and L. Zhu
    Biotechnol Bioeng Vol. 116 (9) 2156-2166 (2019)
    https://www.doi.org/10.1002/bit.27011
  • Publication

    Ultrahigh-throughput screening system for directed polymer binding peptide evolution

    L. Apitius, K. Rubsam, C. Jakesch, F. Jakob and U. Schwaneberg
    Biotechnol Bioeng Vol. 116 (8) 1856-1867 (2019)
    https://www.doi.org/10.1002/bit.26990
  • Publication

    Biadhesive Peptides for Assembling Stainless Steel and Compound Loaded Micro-Containers

    L. Apitius, S. Buschmann, C. Bergs, D. Schonauer, F. Jakob, A. Pich and U. Schwaneberg
    Macromol Biosci e1900125 (2019)
    https://www.doi.org/10.1002/mabi.201900125
  • Publication

    Consensus model of a cyanobacterial light-dependent protochlorophyllide oxidoreductase in its pigment-free apo-form and photoactive ternary complex

    J. Schneidewind, F. Krause, M. Bocola, A. M. Stadler, M. D. Davari, U. Schwaneberg, K.-E. Jaeger and U. Krauss
    Communications Biology Vol. 2 (1) 351 (2019)
    https://www.doi.org/10.1038/s42003-019-0590-4
  • Publication

    Computer-assisted Recombination (CompassR) teaches us how to recombine beneficial substitutions from directed evolution campaigns

    H. Cui, H. Cao, H. Cai, J. Karl-Erich, M. D. Davari and U. Schwaneberg
    Chemistry – A European Journal Vol. 0 (0) (2019)
    https://www.doi.org/10.1002/chem.201903994
  • Publication

    Matter-tag: A universal immobilization platform for enzymes on polymers, metals, and silicon-based materials

    S. Dedisch, A. Wiens, M. D. Davari, D. Söder, C. Rodriguez-Emmenegger, F. Jakob and U. Schwaneberg
    Biotechnology and Bioengineering Vol. 117 (1) (2019)
    https://www.doi.org/10.1002/bit.27181
  • Publication

    Selective Functionalization of Microgels with Enzymes by Sortagging

    Z. Zou, E. Gau, I. El-Awaad, F. Jakob, A. Pich and U. Schwaneberg
    Bioconjugate Chemistry Vol. 30 (11) 2859-2869 (2019)
    https://www.doi.org/10.1021/acs.bioconjchem.9b00568
  • Publication

    Critical effect of proline on thermostability of endoglucanase II from Penicillium verruculosum

    A. S. Dotsenko, S. Pramanik, A. V. Gusakov, A. M. Rozhkova, I. N. Zorov, A. P. Sinitsyn, M. D. Davari and U. Schwaneberg
    Biochemical Engineering Journal Vol. 152 107395 (2019)
    https://doi.org/10.1016/j.bej.2019.107395
  • Publication

    Chemoenzymatic cascade for stilbene production from cinnamic acid catalyzed by ferulic acid decarboxylase and an artificial metathease

    M. A. S. Mertens, D. F. Sauer, U. Markel, J. Schiffels, J. Okuda and U. Schwaneberg
    Catalysis Science & Technology Vol. 9 (20) 5572-5576 (2019)
    https://www.doi.org/10.1039/C9CY01412H
  • Publication

    One-Pot Two-Step Chemoenzymatic Cascade for the Synthesis of a Bis-benzofuran Derivative

    M. A. S. Mertens, F. Thomas, M. Nöth, J. Moegling, I. El-Awaad, D. F. Sauer, G. V. Dhoke, W. Xu, A. Pich, S. Herres-Pawlis and U. Schwaneberg
    European Journal of Organic Chemistry Vol. 2019 (37) 6341-6346 (2019)
    https://www.doi.org/10.1002/ejoc.201900904
  • Publication

    Rapid and Robust Coating Method to Render Polydimethylsiloxane Surfaces Cell-Adhesive

    D. B. Gehlen, L. C. De Lencastre Novaes, W. Long, A. J. Ruff, F. Jakob, T. Haraszti, Y. Chandorkar, L. Yang, P. van Rijn, U. Schwaneberg and L. De Laporte
    ACS Appl Mater Interfaces (2019)
    https://www.doi.org/10.1021/acsami.9b16025
  • Publication

    A bifunctional dermaseptin–thanatin dipeptide functionalizes the crop surface for sustainable pest management

    P. Schwinges, S. Pariyar, F. Jakob, M. Rahimi, L. Apitius, M. Hunsche, L. Schmitt, G. Noga, C. Langenbach, U. Schwaneberg and U. Conrath
    Green Chemistry Vol. 21 (9) 2316-2325 (2019)
    https://www.doi.org/10.1039/C9GC00457B
  • Publication

    How To Engineer Ionic Liquids Resistant Enzymes: Insights from Combined Molecular Dynamics and Directed Evolution Study

    S. Pramanik, G. V. Dhoke, K.-E. Jaeger, U. Schwaneberg and M. D. Davari
    ACS Sustainable Chemistry & Engineering Vol. 7 (13) 11293-11302 (2019)
    https://www.doi.org/10.1021/acssuschemeng.9b00752
  • Publication

    Turning a Killing Mechanism into an Adhesion and Antifouling Advantage

    S. Dedisch, F. Obstals, A. de los Santos Pereira, M. Bruns, F. Jakob, U. Schwaneberg and C. Rodriguez-Emmenegger
    Advanced Materials Interfaces Vol. 6 (18) 1900847 (2019)
    https://www.doi.org/10.1002/admi.201900847
  • Publication

    Depolymerization of Laccase-Oxidized Lignin in Aqueous Alkaline Solution at 37 °C

    H. Liu, L. Zhu, A.-M. Wallraf, C. Räuber, P. M. Grande, N. Anders, C. Gertler, B. Werner, J. Klankermayer, W. Leitner and U. Schwaneberg
    ACS Sustainable Chemistry & Engineering Vol. 7 (13) 11150-11156 (2019)
    https://www.doi.org/10.1021/acssuschemeng.9b00204
  • Publication

    Biocatalyst Immobilization by Anchor Peptides on an Additively Manufacturable Material

    N. Büscher, G. V. Sayoga, K. Rübsam, F. Jakob, U. Schwaneberg, S. Kara and A. Liese
    Organic Process Research & Development Vol. 23 (9) 1852-1859 (2019)
    https://www.doi.org/10.1021/acs.oprd.9b00152
  • Publication

    A 96-multiplex capillary electrophoresis screening platform for product based evolution of P450 BM3

    A. Gartner, A. J. Ruff and U. Schwaneberg
    Scientific Reports Vol. 9 (2019)
    https://www.doi.org/10.1038/s41598-019-52077-w
  • Publication

    Advances in ultrahigh-throughput screening for directed enzyme evolution

    U. Markel, K. D. Essani, V. Besirlioglu, J. Schiffels, W. R. Streit and U. Schwaneberg
    Chemical Society Reviews Vol. 49 (1) 233-262 (2019)
    https://pubs.rsc.org/en/content/articlelanding/2020/cs/c8cs00981c#!divAbstract
  • Publication

    Engineering Robust Cellulases for Tailored Lignocellulosic Degradation Cocktails

    F. Contreras; S. Pramanik; A. Rozhkova; I. Zorov; O. Korotkova; A. Sinitsyn; U. Schwaneberg; M. Davari
    International Journal of Molecular Sciences Vol. 21 (5) 1589 (2020)
    https://doi.org/10.3390/ijms21051589
  • Publication

    Phytase-Based Phosphorus Recovery Process for 20 Distinct Press Cakes

    K. R. Herrmann, A. J. Ruff and U. Schwaneberg
    ACS Sustainable Chemistry & Engineering Vol. 8 (9) 3913-3921 (2020)
    https://doi.org/10.1021/acssuschemeng.9b07433
  • Publication

    Engineering of Laccase CueO for Improved Electron Transfer in Bioelectrocatalysis by Semi-Rational Design

    L. Zhang, H Cui, G. Dhoke, Z. Zou, D. Sauer, M. Davari and U. Schwaneberg
    Chemistry – A European Journal Vol. 26 (22) 4974-4979 (2020)
    https://doi.org/10.1002/chem.201905598
  • Publication

    Effects of Proline Substitutions on the Thermostable LOV Domain from Chloroflexus aggregans

    A. Remeeva, V. Nazarenko, I. Goncharov, A. Yudenko, A. Smolentseva, O. Semenov, K. Kovalev, C. Gülbahar, U. Schwaneberg, M. Davari, V. Gordeliy and I. Gushchin
    Crystals Vol. 10 (4) 256 (2020)
    https://doi.org/10.3390/cryst10040256
  • Publication

    Loop engineering of aryl sulfotransferase B for improving catalytic performance in regioselective sulfation

    Y. Ji, S. Islam, H. Cui, G. Dhoke, M. Davari, A. M. Mertensa and U. Schwaneberg
    Catalysis Science & Technology Vol. 10 (8) 2369-2377 (2020)
    https://doi.org/10.1039/D0CY00063A
  • Publication

    How to Engineer Organic Solvent Resistant Enzymes: Insights from Combined Molecular Dynamics and Directed Evolution Study

    H. Cui, T. H. J. Stadtmüller, Q. Jiang, K. Jaeger, U. Schwaneberg and M. D. Davari
    ChemCatChem Vol. 12 (16) 4073-4083 (2020)
    https://doi.org/10.1002/cctc.202000422
  • Publication

    Engineered P450 BM3 and cpADH5 coupled cascade reaction for beta-oxo fatty acid methyl ester production in whole cells

    Y. Ensari, G. de Almeida Santos, A. J. Ruff and U. Schwaneberg
    Enzyme and Microbial Technology Vol. 138 109555 (2020)
    https://doi.org/10.1016/j.enzmictec.2020.109555
  • Publication

    Enhancing Robustness of Sortase A by Loop Engineering and Backbone Cyclization

    Z. Zou, D. M. Mate, M. Noth, F. Jakob and U. Schwaneberg
    Chemistry-a European Journal Vol. 26 (60) 13568-13572 (2020)
    https://doi.org/10.1002/chem.202002740
  • Publication

    KnowVolution of a GH5 Cellulase from Penicillium verruculosum to Improve Thermal Stability for Biomass Degradation

    F. Contreras, M. J. Thiele, S. Pramanik, A. M. Rozhkova, A. S. Dotsenko, I. N. Zorov, A. P. Sinitsyn, M. D. Davari and U. Schwaneberg
    Acs Sustainable Chemistry & Engineering Vol. 8 (33) 12388-12399 (2020)
    https://doi.org/10.1021/acssuschemeng.0c02465
  • Publication

    FhuA-Grubbs-Hoveyda Biohybrid Catalyst Embedded in a Polymer Film Enables Catalysis in Neat Substrates

    T. M. Garakani, D. F. Sauer, M. A. S. Mertens, J. Lazar, J. Gehrmann, M. Arlt, J. Schiffels, U. Schnakenberg, J. Okuda and U. Schwaneberg
    ACS Catalysis Vol. 10 (19) 10946-10953 (2020)
    https://doi.org/10.1021/acscatal.0c03055
  • Publication

    Biocatalytic microgels (μ-Gelzymes): synthesis, concepts, and emerging applications

    M. Nöth, E. Gau, F. Jung, M. D. Davari, I. El-Awaad, A. Pich and U. Schwaneberg
    Green Chemistry Vol. 22 (23) 8183-8209 (2020)
    https://doi.org/10.1039/D0GC03229H
  • Publication

    MicroGelzymes: pH-Independent Immobilization of Cytochrome P450 BM3 in Microgels

    M. Nöth, L. Hussmann, T. Belthle, I. El-Awaad, M. D. Davari, F. Jakob, A. Pich and U. Schwaneberg
    Biomacromolecules Vol. 21 (12) 5128-5138 (2020)
    https://doi.org/10.1021/acs.biomac.0c01262
  • Publication

    Designed Streptococcus pyogenes Sortase A Accepts Branched Amines as Nucleophiles in Sortagging

    Z. Zou, M. Nöth, F. Jakob and U. Schwaneberg
    Bioconjugate Chemistry Vol. 31 (11) 2476-2481 (2020)
    https://doi.org/10.1021/acs.bioconjchem.0c00486
  • Publication

    A peptide-based coating toolbox to enable click chemistry on polymers, metals, and silicon through sortagging

    M. Nöth, Z. Zou, I. El-Awaad, L. C. de Lencastre Novaes, G. Dilarri, M. D. Davari, H. Ferreira, F. Jakob and U. Schwaneberg
    Bioengineering (2021)
    https://doi.org/10.1002/bit.27666
  • Publication

    CompassR Yields Highly Organic-Solvent-Tolerant Enzymes through Recombination of Compatible Substitutions

    H. Cui, K.-E. Jaeger, M. D. Davari and U. Schwaneberg
    Chemistry – A European Journal Vol. 27 (8) 2789-2797 (2020)
    https://doi.org/10.1002/chem.202004471
  • Publication

    Rapid and Oriented Immobilization of Laccases on Electrodes via a Methionine-Rich Peptide

    H. Cui, L. Zhang, D. Söder, X. Tang, M. D. Davari and U. Schwaneberg
    ACS Catalysis Vol. 11 (4) 2445-2453 (2021)
    https://doi.org/10.1021/acscatal.0c05490
  • Publication

    Less Unfavorable Salt Bridges on the Enzyme Surface Result in More Organic Cosolvent Resistance

    H. Cui, L. Eltoukhy, L. Zhang, U. Markel, K.-E. Jaeger, M. D. Davari and U. Schwaneberg
    Angewandte Chemie International Edition (2021)
    https://doi.org/10.1002/anie.202101642
  • Publication

    Tunnel engineering for modulating the substrate preference in cytochrome P450BsβHI

    S. Meng, R. An, Z. Li, U. Schwaneberg, Y. Ji, M. D. Davari, F. Wang, M. Wang, M. Qin, K. Nie and L. Liu
    Bioresources and Bioprocessing Vol. 8 (1) 26 (2021)
    https://doi.org/10.1186/s40643-021-00379-1
  • Publication

    Fe(iii)-complex mediated bacterial cell surface immobilization of eGFP and enzymes

    L. Feng, L. Gao, D. F. Sauer, Y. Ji, H. Cui and U. Schwaneberg
    Chemical Communications Vol. 57 (36) 4460-4463 (2021)
    https://doi.org/10.1039/D1CC01575C
  • Publication

    Understanding substrate binding and the role of gatekeeping residues in PigC access tunnels

    S. Brands, J. G. Sikkens, M. D. Davari, H. U. C. Brass, A. S. Klein, J. Pietruszka, A. J. Ruff and U. Schwaneberg
    Chemical Communications Vol. 57 (21) 2681-2684 (2021)
    https://doi.org/10.1039/D0CC08226K
  • Publication

    CompassR-guided recombination unlocks design principles to stabilize lipases in ILs with minimal experimental efforts

    H. Cui, S. Pramanik, K.-E. Jaeger, M. D. Davari and U. Schwaneberg
    Green Chemistry Vol. 23 (9) 3474-3486 (2021)
    https://doi.org/10.1039/D1GC00763G
  • Publication

    An artificial ruthenium-containing β-barrel protein for alkene–alkyne coupling reaction

    A. Thiel, D. F. Sauer, U. Markel, M. A. S. Mertens, T. Polen, U. Schwaneberg and J. Okuda
    Organic & Biomolecular Chemistry Vol. 19 (13) 2912-2916 (2021)
    https://doi.org/10.1039/D1OB00279A
  • Publication

    KnowVolution of prodigiosin ligase PigC towards condensation of short-chain prodiginines

    S. Brands, H. U. C. Brass, A. S. Klein, J. G. Sikkens, M. D. Davari, J. Pietruszka, A. J. Ruff and U. Schwaneberg
    Catalysis Science & Technology Vol. 11 (8) 2805-2815 (2021)
    https://doi.org/10.1039/D0CY02297G
  • Publication

    Chemogenetic engineering of nitrobindin toward an artificial epoxygenase

    D. F. Sauer, M. Wittwer, U. Markel, A. Minges, M. Spiertz, J. Schiffels, M. D. Davari, G. Groth, J. Okuda and U. Schwaneberg
    Catalysis Science & Technology Vol. 11 (13) 4491-4499 (2021)
    https://doi.org/10.1039/D1CY00609F
  • Publication

    Chemogenetic Evolution of a Peroxidase-like Artificial Metalloenzyme

    U. Markel, D. F. Sauer, M. Wittwer, J. Schiffels, H. Cui, M. D. Davari, K. W. Kröckert, S. Herres-Pawlis, J. Okuda and U. Schwaneberg
    ACS Catalysis Vol. 11 (9) 5079-5087 (2021)
    https://doi.org/10.1021/acscatal.1c00134
  • Publication

    Systematically Scrutinizing the Impact of Substitution Sites on Thermostability and Detergent Tolerance for Bacillus subtilis Lipase A

    C. Nutschel, A. Fulton, O. Zimmermann, U. Schwaneberg, K.-E. Jaeger and H. Gohlke
    Journal of Chemical Information and Modeling Vol. 60 (3) 1568-1584 (2020)
    https://doi.org/10.1021/acs.jcim.9b00954
  • Publication

    A colourimetric high-throughput screening system for directed evolution of prodigiosin ligase PigC

    S. Brands, H. U. C. Brass, A. S. Klein, J. Pietruszka, A. J. Ruff and U. Schwaneberg
    Chemical Communications Vol. 56 (61) 8631-8634 (2020)
    https://doi.org/10.1039/d0cc02181d
  • Publication

    Display of functional nucleic acid polymerase on Escherichia coli surface and its application in directed polymerase evolution

    M.-E. Chung, K. Goroncy, A. Kolesnikova, D. Schönauer and U. Schwaneberg
    Biotechnology and Bioengineering Vol. 117 (12) 3699-3711 (2020)
    https://doi.org/10.1002/bit.27542
  • Publication

    A Photoclick-Based High-Throughput Screening for the Directed Evolution of Decarboxylase OleT

    U. Markel, P. Lanvers, D. F. Sauer, M. Wittwer, G. V. Dhoke, M. D. Davari, J. Schiffels and U. Schwaneberg
    Chemistry – A European Journal Vol. 27 (3) 954-958 (2020)
    https://doi.org/10.1002/chem.202003637
  • Publication

    Insights on intermolecular FMN-heme domain interaction and the role of linker length in cytochrome P450cin fusion proteins

    K. D. Belsare, A. J. Ruff, R. Martinez and U. Schwaneberg
    Biological Chemistry Vol. 401 (11) 1249-1255 (2020)
    https://doi.org/10.1515/hsz-2020-0134
  • Publication

    Enzyme Hydration Determines Resistance in Organic Cosolvents

    H. Cui, L. Zhang, L. Eltoukhy, Q. Jiang, S. K. Korkunç, K.-E. Jaeger, U. Schwaneberg and M. D. Davari
    ACS Catalysis Vol. 10 (24) 14847-14856 (2020)
    https://doi.org/10.1021/acscatal.0c03233
  • Publication

    Chapter Twelve - Machine learning-assisted enzyme engineering

    N. E. Siedhoff, U. Schwaneberg and M. D. Davari
    Methods in Enzymology [Book] Vol. 643 281-315 (2020)
    https://doi.org/10.1016/bs.mie.2020.05.005
  • Publication

    Directed evolution of VanR biosensor specificity in yeast

    V. D'Ambrosio, S. Pramanik, K. Goroncy, T. Jakočiūnas, D. Schönauer, M. D. Davari, U. Schwaneberg, J. D. Keasling and M. K. Jensen
    Biotechnology Notes Vol. 1 9-15 (2020)
    https://doi.org/10.1016/j.biotno.2020.01.002
  • Publication

    Can constraint network analysis guide the identification phase of KnowVolution? A case study on improved thermostability of an endo-β-glucanase

    F. Contreras, C. Nutschel, L. Beust, M. D. Davari, H. Gohlke and U. Schwaneberg
    Computational and Structural Biotechnology Journal Vol. 19 743-751 (2020)
    https://doi.org/10.1016/j.csbj.2020.12.034
  • Publication

    Unraveling the Mechanism and Kinetics of Binding of an LCI-eGFP-Polymer for Antifouling Coatings

    D. Söder, M. Garay-Sarmiento, K. Rahimi, F. Obstals, S. Dedisch, T. Haraszti, M. D. Davari, F. Jakob, C. Heß, U. Schwaneberg and C. Rodriguez-Emmenegger
    Macromolecular Bioscience 2100158 (2021)
    https://doi.org/10.1002/mabi.202100158
  • Publication

    Aqueous Ionic Liquids Redistribute Local Enzyme Stability Via Long-Range Perturbation Pathways

    T. El Harrar, B. Frieg, M. D. Davari, K.-E. Jaeger, U. Schwaneberg and H. Gohlke
    Computational and Structural Biotechnology Journal Vol. 19 4248-4264 (2021)
    https://doi.org/10.1016/j.csbj.2021.07.001
  • Publication

    Generation of Phytase Chimeras with Low Sequence Identities and Improved Thermal Stability

    K. R. Herrmann, I. Hofmann, D. Jungherz, M. Wittwer, B. Infanzón, S. N. Hamer, M. D. Davari, A. J. Ruff and U. Schwaneberg
    Journal of Biotechnology Vol. 339 14-21 (2021)
    https://doi.org/10.1016/j.jbiotec.2021.07.005
  • Publication

    The Molecular Basis of Spectral Tuning in Blue- and Red-Shifted Flavin-Binding Fluorescent Proteins

    K. Röllen, J. Granzin, A. Remeeva, M. D. Davari, T. Gensch, V. V. Nazarenko, K. Kovalev, A. Bogorodskiy, V. Borshchevskiy, S. Hemmer, U. Schwaneberg, V. Gordeliy, K.-E. Jaeger, R. Batra-Safferling, I. Gushchin and U. Krauss
    Journal of Biological Chemistry Vol. 296 100662 (2021)
    https://doi.org/10.1016/j.jbc.2021.100662
  • Publication

    Enzyme Mimetic Microgel Coating for Endogenous Nitric Oxide Mediated Inhibition of Platelet Activation

    A. Hosseinnejad, T. Fischer, P. Jain, C. Bleilevens, F. Jakob, U. Schwaneberg, R. Rossaint and S. Singh
    Journal of Colloid and Interface Science Vol. 601 604-616 (2021)
    https://doi.org/10.1016/j.jcis.2021.05.143
  • Publication

    Pypef—an Integrated Framework for Data-Driven Protein Engineering

    N. E. Siedhoff, A.-M. Illig, U. Schwaneberg and M. D. Davari
    Journal of Chemical Information and Modeling Vol. 61 (7) 3463-3476 (2021)
    https://doi.org/10.1021/acs.jcim.1c00099
  • Publication

    Expression and Refolding of the Plant Chitinase from Drosera Capensis for Applications as a Sustainable and Integrated Pest Management

    I. G. Sinelnikov, N. E. Siedhoff, A. M. Chulkin, I. N. Zorov, U. Schwaneberg, M. D. Davari, O. A. Sinitsyna, L. A. Shcherbakova, A. P. Sinitsyn and A. M. Rozhkova
    Frontiers in Bioengineering and Biotechnology Vol. 9 (862) (2021)
    https://doi.org/10.3389/fbioe.2021.728501
  • Publication

    Chapter Thirteen - Anchor Peptides Promote Degradation of Mixed Plastics for Recycling

    Y. Ji, Y. Lu, H. Puetz and U. Schwaneberg
    Methods in Enzymology Vol. 648 271-292 (2021)
    https://doi.org/10.1016/bs.mie.2020.12.027
  • Publication

    Protein Engineering by Efficient Sequence Space Exploration through Combination of Directed Evolution and Computational Design Methodologies

    S. Pramanik, F. Contreras, M. D. Davari and U. Schwaneberg
    Protein Engineering: Tools and Applications 153-176 (2021)
    https://doi.org/10.1002/9783527815128.ch7
  • Publication

    Kill&Repel Coatings: The Marriage of Antifouling and Bactericidal Properties to Mitigate and Treat Wound Infections

    M. Garay-Sarmiento, L. Witzdam, M. Vorobii, C. Simons, N. Herrmann, A. de los Santos Pereira, E. Heine, I. El-Awaad, R. Lütticken, F. Jakob, U. Schwaneberg and C. Rodriguez-Emmenegger
    Advanced Functional Materials 2106656 (2021)
    https://doi.org/10.1002/adfm.202106656
  • Publication

    Engineering and Emerging Applications of Artificial Metalloenzymes with Whole Cells

    M. Wittwer, U. Markel, J. Schiffels, J. Okuda, D. F. Sauer and U.
    Nature Catalysis Vol. 4 (10) 814-827 (2021)
    https://doi.org/10.1038/s41929-021-00673-3
  • Publication

    Dnase I Functional Microgels for Neutrophil Extracellular Trap Disruption

    A. Hosseinnejad, N. Ludwig, A.-K. Wienkamp, R. Rimal, C. Bleilevens, R. Rossaint, J. Rossaint and S. Singh
    Biomaterials Science Vol. 10 (1) 85-99 (2021)
    https://doi.org/10.1039/D1BM01591E
  • Publication

    Protein Nanopore Membranes Prepared by a Simple Langmuir–Schaefer Approach

    M. S. Schwieters, M. Mathieu-Gaedke, M. Westphal, R. Dalpke, M. Dirksen, D. Qi, M. Grull, T. Bick, S. Taßler, D. F. Sauer, M. Bonn, P. Wendler, T. Hellweg, A. Beyer, A. Gölzhäuser, U. Schwaneberg, U. Glebe and A. Böker
    Advanced Materials Vol. 17 (46) 2102975 (2021)
    https://doi.org/10.1002/smll.202102975
  • Publication

    Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design

    E. Rajakumara, S. Abhishek, K. Nitin, D. Saniya, P. Bajaj, U. Schwaneberg and M. D. Davari
    ACS Chemical Biology Vol. 17 (2) 266–280 (2022)
    https://doi.org/10.1021/acschembio.1c00500
  • Publication

    Endogenous Nitric Oxide-Releasing Microgel Coating Prevents Clot Formation on Oxygenator Fibers Exposed to in Vitro Blood Flow

    P. Winnersbach, A. Hosseinnejad, T. Breuer, T. Fechter, F. Jakob, U. Schwaneberg, R. Rossaint, C. Bleilevens and S. Singh
    Membranes (Basel) Vol. 12 (1) 73 (2022)
    https://doi.org/10.3390/membranes12010073
  • Publication

    Polar Substitutions on the Surface of a Lipase Substantially Improve Tolerance in Organic Solvents

    H. Cui, M. Vedder, L. Zhang, K.-E. Jaeger, U. Schwaneberg and M. D. Davari
    ChemSusChem (2022)
    https://doi.org/10.1002/cssc.202102551
  • Publication

    In Silico and Experimental Adam17 Kinetic Modeling as Basis for Future Screening System for Modulators

    M. Bienstein, D. Minond, U. Schwaneberg, M. D. Davari and D. Yildiz
    International Journal of Molecular Sciences Vol. 23 (3) 1368 (2022)
    https://doi.org/10.3390/ijms23031368
  • Publication

    A Plea for the Integration of Green Toxicology in Sustainable Bioeconomy Strategies – Biosurfactants and Microgel-Based Pesticide Release Systems as Examples

    S. Johann, F. G. Weichert, L. Schröer, L. Stratemann, C. Kämpfer, T.-B. Seiler, S. Heger, A. Töpel, T. Sassmann, A. Pich, F. Jakob, U. Schwaneberg, P. Stoffels, M. Philipp, M. Terfrüchte, A. Loeschcke, K. Schipper, M. Feldbrügge, N. Ihling, J. Büchs, I. Bator, T. Tiso, L. M. Blank, M. Roß-Nickoll and H. Hollert
    Journal of Hazardous Materials Vol. 426 127800 (2022)
    https://doi.org/10.1016/j.jhazmat.2021.127800
  • Publication

    Preparative Production of Functionalized (N- and O-Heterocyclic) Polycyclic Aromatic Hydrocarbons by Human Cytochrome P450 3A4 in a Bioreactor

    M. Srdič, N. D. Fessner, D. Yildiz, A. Glieder, M. Spiertz and U. Schwaneberg
    Biomolecules Vol. 12 (2) 153 (2022)
    https://doi.org/10.3390/biom12020153
  • Publication

    Optimized Hemolysin Type 1 Secretion System in Escherichia Coli by Directed Evolution of the Hly Enhancer Fragment and Including a Terminator Region

    Z. Pourhassan N., H. Cui, S. Khosa, M. D. Davari, K.-E. Jaeger, S. H. J. Smits, U. Schwaneberg and L. Schmitt
    ChemBioChem e202100702 (2022)
    https://doi.org/10.1002/cbic.202100702
  • Publication

    Recombination of Compatible Substitutions by 2GenReP and InSiReP

    H. Cui, M. D. Davari and U. Schwaneberg
    Enzyme Engineering 71-81 (2021)
    https://doi.org/10.1007/978-1-0716-1826-4_5
  • Publication

    Using Molecular Simulation to Guide Protein Engineering for Biocatalysis in Organic Solvents

    H. Cui, M. Vedder, U. Schwaneberg and M. D. Davari
    Enzyme Engineering 179-202 (2021)
    https://doi.org/10.1007/978-1-0716-1826-4_10
  • Publication

    Phytase Blends for Enhanced Phosphorous Mobilization of Deoiled Seeds

    B. Infanzón, K. R. Herrmann, I. Hofmann, S. Willbold, A. J. Ruff and U. Schwaneberg
    Enzyme and Microbial Technology Vol. 153 109953 (2021)
    https://doi.org/10.1016/j.enzmictec.2021.109953
  • Publication

    Critical Assessment of Structure-Based Approaches to Improve Protein Resistance in Aqueous Ionic Liquids by Enzyme-Wide Saturation Mutagenesis

    T. El Harrar, M. D. Davari, K.-E. Jaeger, U. Schwaneberg and H. Gohlke
    Computational and Structural Biotechnology Journal Vol. 20 399-409 (2021)
    https://doi.org/10.1016/j.csbj.2021.12.018
  • Publication

    Bioadhere: Tailor-Made Bioadhesives for Epiretinal Visual Prostheses

    K.-W. Hintzen, C. Simons, K. Schaffrath, G. Roessler, S. Johnen, F. Jakob, P. Walter, U. Schwaneberg and T. Lohmann
    Biomaterials Science (2022)
    https://doi.org/10.1039/D1BM01946E
  • Publication

    Combinatorial Invitroflow-Assisted Mutagenesis (Combimut) Yields a 41-Fold Improved Cela2 Cellulase

    G. Körfer, V. Besirlioglu, M. D. Davari, R. Martinez, L. Vojcic and U. Schwaneberg
    Biotechnology and Bioengineering (2022)
    https://doi.org/10.1002/bit.28110
  • Publication

    Flexibility Regulation of Loops Surrounding the Tunnel Entrance in Cytochrome P450 Enhanced Substrate Access Substantially

    Z. Li, S. Meng, K. Nie, U. Schwaneberg, M. D. Davari, H. Xu, Y. Ji and L. Liu
    ACS Catalysis Vol. 12 (20) 12800-12808 (2022)
    https://doi.org/10.1021/acscatal.2c02258
  • Publication

    Using a Bio-Economic Farm Model to Evaluate the Economic Potential and Pesticide Load Reduction of the Greenrelease Technology

    T. Kuhn, N. Möhring, A. Töpel, F. Jakob, W. Britz, S. Bröring, A. Pich, U. Schwaneberg and M. Rennings
    Agricultural Systems Vol. 201 103454 (2022)
    https://doi.org/10.1016/j.agsy.2022.103454
  • Publication

    Enzyme Hydration: How to Retain Resistance in Ionic Liquids

    H. Cui, L. Zhang, C. B. Yildiz, L. Eltoukhy, L. Cheng, K.-E. Jaeger, U. Schwaneberg and M. D. Davari
    ACS Sustainable Chemistry & Engineering (2022)
    https://doi.org/10.1021/acssuschemeng.2c04216
  • Publication

    The Molecular Basis and Enzyme Engineering Strategies for Improvement of Coupling Efficiency in Cytochrome P450s

    S. Meng, Y. Ji, L. Zhu, G. V. Dhoke, M. D. Davari and U. Schwaneberg
    Biotechnology Advances Vol. 61 108051 (2022)
    https://doi.org/10.1016/j.biotechadv.2022.108051
  • Publication

    Rational Design Yields Molecular Insights on Leaf-Binding of Anchor Peptides

    J. Dittrich, C. Brethauer, L. Goncharenko, J. Bührmann, V. Zeisler-Diehl, S. Pariyar, F. Jakob, T. Kurkina, L. Schreiber, U. Schwaneberg and H. Gohlke
    ACS Applied Materials & Interfaces Vol. 14 (25) 28412-28426 (2022)
    https://doi.org/10.1021/acsami.2c00648
  • Publication

    How Does Surface Charge Engineering of Bacillus subtilis Lipase A Improve Ionic Liquid Resistance? Lessons Learned from Molecular Dynamics Simulations

    Subrata Pramanik, Haiyang Cui, Gaurao V. Dhoke, Can Bora Yildiz, Markus Vedder, Karl-Erich Jaeger, Ulrich Schwaneberg, and Mehdi D. Davari
    ACS Sustainable Chemistry & Engineering Vol. 10 (8) 2689 - 2698 (2022)
    https://doi.org/10.1021/acssuschemeng.1c07332
  • Publication

    Recombination of Single Beneficial Substitutions Obtained from Protein Engineering by Computer-Assisted Recombination (CompassR)

    H. Cui, M. D. Davari and U. Schwaneberg
    Directed Evolution: Methods and Protocols 9 - 18 (2022)
    https://doi.org/10.1007/978-1-0716-2152-3_2
  • Publication

    Modulating the Coupling Efficiency of P450 BM3 by Controlling Water Diffusion through Access Tunnel Engineering

    Shuaiqi Meng, Dr. Yu Ji, Prof. Luo Liu, Dr. Mehdi D. Davari and Ulrich Schwaneberg
    ChemSusChem Vol. 15 (9) e202102434 (2022)
    https://doi.org/10.1002/cssc.202102434
  • Publication

    Evolution of E. coli Phytase Toward Improved Hydrolysis of Inositol Tetraphosphate

    Kevin R. Herrmann, Christin Brethauer, Niklas E. Siedhof, Isabell Hofman, Johanna Eyl, Mehdi D. Davar, Ulrich Schwaneberg and Anna Joëlle Ruff
    Frontiers in Chemical Engineering Vol. 4 9 (2022)
    https://doi.org/10.3389/fceng.2022.838056
  • Publication

    Transformative Materials for Interfacial Drug Delivery

    P. Desai, A. Dasgupta, A. M. Sofias, Q. Peña, R. Göstl, I. Slabu, U. Schwaneberg, T. Stiehl, W. Wagner, S. Jockenhövel, J. Stingl, R. Kramann, C. Trautwein, T. H. Brümmendorf, F. Kiessling, A. Herrmann and T. Lammers
    Advanced Healthcare Materials 2301062 (2023)
    https://doi.org/10.1002/adhm.202301062
  • Publication

    Hexyl Gallate Loaded Microgels Enable Efficient Protection Against Citrus Canker

    S. Braun, G. Dilarri, L. C. de Lencastre Novaes, P. Huth, A. Töpel, L. Hussmann, A. Boes, M. D. da Rocha, F. Jakob, L. O. Regasini, U. Schwaneberg, H. Ferreira and A. Pich
    Advanced Functional Materials 2305646 (2023)
    https://doi.org/10.1002/adfm.202305646
  • Publication

    Machine Learning-Assisted Engineering of Light, Oxygen, Voltage Photoreceptor Adduct Lifetime

    S. Hemmer, N. E. Siedhoff, S. Werner, G. Ölçücü, U. Schwaneberg, K.-E. Jaeger, M. D. Davari and U. Krauss
    JACS Au Vol. 3 (12) 3311-3323 (2023)
    https://doi.org/10.1021/jacsau.3c00440
  • Publication

    Brush-Like Coatings Provide a Cloak of Invisibility to Titanium Implants

    L. Witzdam, M. Garay-Sarmiento, M. Gagliardi, Y. L. Meurer, Y. Rutsch, J. Englert, S. Philipsen, A. Janem, R. Alsheghri, F. Jakob, D. G. M. Molin, U. Schwaneberg, N. M. S. van den Akker and C. Rodriguez-Emmenegger
    Macromolecular Bioscience 2300434 (2023)
    https://doi.org/10.1002/mabi.202300434
  • Publication

    Novel Multienzyme Cascade for Efficient Synthesis of D-Allulose from Inexpensive Sucrose

    R. Han, W. Tu, S. Liu, Y. Ji, U. Schwaneberg, Y. Guo and Y. Ni
    Food Bioscience Vol. 56 103303 (2023)
    https://doi.org/10.1016/j.fbio.2023.103303
  • Publication

    Surface Engineering of Cyclodextrin Glycosyltransferase Reveals Structural Compactness and Rigidity Responsible for Enhanced Organic Solvents Resistance

    R. Han, Y. Jiang, S. Liu, Y. Ji, U. Schwaneberg and Y. Ni
    Molecular Catalysis Vol. 550 113613 (2023)
    https://doi.org/10.1016/j.mcat.2023.113613
  • Publication

    A Phylogeny-Based Directed Evolution Approach to Boost the Synthetic Applications of Glycosyltransferases

    P. Zhang, Y. Ji, S. Meng, Z. Li, D. Hirtz, L. Elling and U. Schwaneberg
    Green Chemistry Vol. 25 (20) 8108-8116 (2023)
    https://doi.org/10.1039/D3GC01259J
  • Publication

    Directed Evolution of Material Binding Peptide for Polylactic Acid-Specific Degradation in Mixed Plastic Wastes

    Y. Lu, K.-W. Hintzen, T. Kurkina, Y. Ji and U. Schwaneberg
    ACS Catalysis Vol. 13 (19) 12746-12754 (2023)
    https://doi.org/10.1021/acscatal.3c02142
  • Publication

    Empowering Site-Specific Bioconjugations in Vitro and in Vivo: Advances in Sortase Engineering and Sortase-Mediated Ligation

    Z. Zou, Y. Ji and U. Schwaneberg
    Angewandte Chemie International Edition e202310910 (2023)
    https://doi.org/10.1002/anie.202310910
  • Publication

    Engineering of Substrate Tunnel of P450 Cyp116b3 Though Machine Learning

    Y. Liu, Z. Li, C. Cao, X. Zhang, S. Meng, M. D. Davari, H. Xu, Y. Ji, U. Schwaneberg and L. Liu
    Catalysts Vol. 13 (8) 1228 (2023)
    https://doi.org/10.3390/catal13081228
  • Publication

    A Competitive High-Throughput Screening Platform for Designing Polylactic Acid-Specific Binding Peptides

    Y. Lu, K.-W. Hintzen, T. Kurkina, Y. Ji and U. Schwaneberg
    Advanced Science 2303195 (2023)
    https://doi.org/10.1002/advs.202303195
  • Publication

    Validated High-Throughput Screening System for Directed Evolution of Nylon-Depolymerizing Enzymes

    H. Puetz, C. Janknecht, F. Contreras, M. Vorobii, T. Kurkina and U. Schwaneberg
    ACS Sustainable Chemistry & Engineering Vol. 11 (43) 15513 - 15522 (2023)
    https://doi.org/10.1021/acssuschemeng.3c01575
  • Publication

    Deep Learning Guided Enzyme Engineering of Thermobifida Fusca Cutinase for Increased Pet Depolymerization

    S. Meng, Z. Li, P. Zhang, F. Contreras, Y. Ji and U. Schwaneberg
    Chinese Journal of Catalysis Vol. 50 229-238 (2023)
    https://doi.org/10.1016/S1872-2067(23)64470-5
  • Publication

    A Step Forward to the Optimized Hlya Type 1 Secretion System through Directed Evolution

    Z. N. Pourhassan, H. Cui, N. Muckhoff, M. D. Davari, S. H. J. Smits, U. Schwaneberg and L. Schmitt
    Applied Microbiology and Biotechnology Vol. 107 (16) 5131-5143 (2023)
    https://doi.org/10.1007/s00253-023-12653-7
  • Publication

    Engineering All-Round Cellulase for Bioethanol Production

    M. Wang, H. Cui, C. Gu, A. Li, J. Qiao, U. Schwaneberg, L. Zhang, J. Wei, X. Li and H. Huang
    ACS Synthetic Biology Vol. 12 (7) 2187-2197 (2023)
    https://doi.org/10.1021/acssynbio.3c00289
  • Publication

    Introduction of Aromatic Amino Acids in Electron Transfer Pathways Yielded Improved Catalytic Performance of Cytochrome P450s

    S. Meng, Z. Li, Y. Ji, A. J. Ruff, L. Liu, M. D. Davari and U. Schwaneberg
    Chinese Journal of Catalysis Vol. 49 81-90 (2023)
    https://doi.org/10.1016/S1872-2067(23)64445-6
  • Publication

    Fhua: From Iron-Transporting Transmembrane Protein to Versatile Scaffolds through Protein Engineering

    D. F. Sauer, U. Markel, J. Schiffels, J. Okuda and U. Schwaneberg
    Accounts of Chemical Research Vol. 56 (12) 1433-1444 (2023)
    https://doi.org/10.1021/acs.accounts.3c00060
  • Publication

    Commentary: Polymer Binding Modules Accelerate Enzymatic Degradation of Poly(Ethylene Terephthalate)

    Y. Lu, R. Han, U. Schwaneberg and Y. Ji
    Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology Vol. 39 (5) 1883-1888 (2023)
    https://doi.org/10.13345/j.cjb.221033
  • Publication

    A Flow Cytometry-Based Ultrahigh-Throughput Screening Method for Directed Evolution of Oxidases

    L. Feng, L. Gao, V. Besirlioglu, K. Essani, M. Wittwer, T. Kurkina, Y. Ji and U. Schwaneberg
    Angewandte Chemie International Edition Vol. 62 (22) e202214999 (2023)
    https://doi.org/10.1002/anie.202214999
  • Publication

    Plastibodies for Multiplexed Detection and Sorting of Microplastic Particles in High-Throughput

    W. Bauten, M. Nöth, T. Kurkina, F. Contreras, Y. Ji, C. Desmet, M.-Á. Serra, D. Gilliland and U. Schwaneberg
    Science of The Total Environment Vol. 860 160450 (2022)
    https://doi.org/10.1016/j.scitotenv.2022.160450
  • Publication

    Bifunctional Peptides as Alternatives to Copper-Based Formulations to Control Citrus Canker

    G. Dilarri, L. C. de Lencastre Novaes, F. Jakob, U. Schwaneberg and H. Ferreira
    Applied Microbiology and Biotechnology Vol. 108 (1) 196 (2024)
    https://doi.org/10.1007/s00253-023-12908-3
  • Publication

    Rational Design of an Artificial Ethylbenzene Hydroxylase Using a Molecular Dynamics Simulation to Enhance Enantioselectivity

    K. Oohora, Y. Kagawa, T. Nishiura, E. Mizohata, U. Schwaneberg and T. Hayashi
    Chemistry Letters Vol. 53 (2) (2023)
    https://doi.org/10.1093/chemle/upad042
  • Publication

    An Enzymatic Continuous-Flow Reactor Based on a Pore-Size Matching Nano- and Isoporous Block Copolymer Membrane

    Z. Zhang, L. Gao, A. Boes, B. Bajer, J. Stotz, L. Apitius, F. Jakob, E. S. Schneider, E. Sperling, M. Held, T. Emmler, U. Schwaneberg and V. Abetz
    Nature Communications Vol. 15 (1) 3308 (2024)
    https://doi.org/10.1038/s41467-024-47007-y
  • Publication

    Adhesion Peptide-Functionalized Biobased Microgels for Controlled Delivery of Pesticides

    A. Yayci, T. Sassmann, A. Boes, F. Jakob, A. Töpel, A. Loreth, C. Rauch, A. Pich and U. Schwaneberg
    Angewandte Chemie International Edition e202319832 (2024)
    https://doi.org/10.1002/anie.202319832
  • Publication

    A Green Peptide-Based Functionalization Platform for Wash Resistant Textile Finishing

    N. Herrmann, A. Boes, F. Jakob and U. Schwaneberg
    Progress in Organic Coatings Vol. 195 108655 (2024)
    https://doi.org/10.1016/j.porgcoat.2024.108655
  • Publication

    Recent Advances in Grating Coupled Surface Plasmon Resonance Technology

    D. Murugan, M. Tintelott, M. S. Narayanan, X.-T. Vu, T. Kurkina, C. Rodriguez-Emmenegger, U. Schwaneberg, J. Dostalek, S. Ingebrandt and V. Pachauri
    Advanced Optical Materials Vol. 12 (34) 2401862 (2024)
    https://doi.org/10.1002/adom.202401862
  • Publication

    Nanoscopic Visualization of Microgel-Immobilized Cytochrome P450 Enzymes and Their Local Activity

    L. Schubert, C. Nenninger, M. Nöth, T. Belthle, R. D. de Lange, A. Pich, U. Schwaneberg and D. Wöll
    Nanoscale Vol. 16 (43) 20194-20201 (2024)
    https://doi.org/10.1039/D4NR03435J
  • Publication

    Toward Antifragile Manufacturing: Concepts from Nature and Complex Human-Made Systems to Gain from Stressors and Volatility

    M. Becker, D. Kasprowicz, T. Kurkina, M. D. Davari, M. Gipperich, G. Gramelsberger, T. Bergs, U. Schwaneberg and D. Trauth
    Transformation Towards Sustainability 425-448 (2024)
    https://doi.org/10.1007/978-3-031-54700-3_16
  • Publication

    Recombinant Supercharged Polypeptide Fusions for the Hydrophilic Finishing of Pet Textiles

    M. Schadt, N. Herrmann, C. Formen, C. Simons, E. Heine, F. Jakob, U. Schwaneberg and A. Herrmann
    ACS Applied Engineering Materials Vol. 2 (11) 2559-2568 (2024)
    https://doi.org/10.1021/acsaenm.4c00489
  • Publication

    Structure Protects Function: A Multilevel Engineered Surface Modification Renders the Surface of Titanium Dental Implants Resistant to Bacterial Colonization

    M. Garay-Sarmiento, A. Yayci, Y. Rutsch, H. El Kadaoui, S. Apelt, J. Englert, A. Boes, M. Kohse, F. Jakob, T. Bergs, U. Schwaneberg and C. Rodriguez-Emmenegger
    ACS Applied Materials & Interfaces Vol. 17 (5) 7498-7509 (2025)
    https://doi.org/10.1021/acsami.4c21111
  • Publication

    Surface-Confined Enzymatic Method for Scalable Thin Film Generation

    C. Nenninger, F. Contreras, M. Vorobii, M. Sárria Pereira de Passos, J. Gebauer, M. Nöth, L. Stütgens, H. El Kadaoui, T. Bergs and U. Schwaneberg
    Surfaces and Interfaces Vol. 60 106046 (2025)
    https://doi.org/10.1016/j.surfin.2025.106046
  • Publication

    Secretory Production of Heterologous Antimicrobial Peptides in Corynebacterium glutamicum

    W. Long, L. Apitius, P. Lenz, F. Jakob, A. J. Ruff  and U. Schwaneberg
    Engineering in Life Sciences Vol. 25 (2) e70008 (2025)
    https://doi.org/10.1002/elsc.70008
  • Publication

    Global Dynamic Design (Gdd) Empowers Cytochrome P450s for Improved Catalytic Performance

    Z. Li, S. Meng, Y. Ji, P. Zhang, B. Nian, C. Zhu, M. D. Davari, H. Xu, U. Schwaneberg and L. Liu
    ACS Sustainable Chemistry & Engineering Vol. 13 (10) 3834-3841 (2025)
    https://doi.org/10.1021/acssuschemeng.4c05423
  • Publication

    Hybrid Pectin-Fibroin Microgels with Supramolecular and Covalent Cross-Links

    G. Kamaraju, J. Karl, S. Bulut, M. Pieper, N. Hazra, G. Chakraborty, A. Boes, A. Herrmann, U. Schwaneberg and A. Pich
    Biomacromolecules Vol. 26 (4) 2331-2343 (2025)
    https://doi.org/10.1021/acs.biomac.4c01658
  • Publication

    Knowvolution of an Efficient Polyamidase through Molecular Dynamics Simulations of Incrementally Docked Oligomeric Substrates

    H. Puetz, A.-M. Illig, M. Vorobii, C. Janknecht, F. Contreras, F. Flemig and U. Schwaneberg
    ChemSusChem 2500257 (2025)
    https://doi.org/10.1002/cssc.202500257

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