Prof. Dr. César Rodriguez-Emmenegger
The research program of the Rodriguez-Emmenegger group focuses in the development of synthetic and biohybrid adaptive interfaces able to interact with the environment drawing inspiration in the way living systems interact and communicate. The group's overarching goal is to understand how to balance the overall repellency with specific multivalent and cooperative attractive interactions to develop superselectivity at interfaces and to translate this to the medical field. Toward this aim synthetic polymer and supramolecular chemistry, physical chemistry, biophysics, and engineering converge in a highly interdisciplinary team. In particular the Emmenegger group is interested in synthesis of macromolecules with precise chemical composition, architecture and topology. These macromolecules are used to study and develop antifouling, antimicrobial surfaces, coatings that interact with blood and modulate uncontrolled coagulation, as well as active synthetic cells.
César Rodriguez-Emmenegger's publications via ORCID
César Rodriguez-Emmenegger's publications via google scholar
Curriculum Vitae
César was born in Salto, in the north of Uruguay. After studying Chemical Engineering (2001—2006) in the Universidad de la Republica he was awarded a research UNESCO-IUPAC internship (2006-2007) in the Institute of Macromolecular Chemistry in Prague where he got hooked in the topic of polymers and biointerfaces. There he pursued his Ph.D. in Biophysics, Chemical and Macromolecular Physics under the supervision of Dr. E. Brynda and Prof. A. Bologna-Alles (2007—2012) working on optical biosensors and antifouling surfaces. Following a postdoctoral research at the group of Prof. C. Barner-Kowollik (Alexander von Humboldt postdoctoral fellowship, 2012-2013), and research stays in Melville Laboratory in Cambridge (Prof. W.T.S. Huck, 2009), University of Pennsylvania (Prof. V. Percec, 2013, 2015) and Pasteur Institute in Lille (Prof. Lafont, 2015), César returned to Prague to start his independent group supported by a Junior Grant from GACR. In January 2016, his group joined DWI and expanded the research to adaptive interfaces and synthetic cells.
Selected professional functions, honors and awards
- 2020 Innovation Sprint RWTH
- 2015 Polymer Chemistry Emerging Investigators 2015 | Royal Society of Chemistry, UK
- 2014 Japan Society for the Promotin of Science, Postdoctoral Fellowship for North Americam and European Researches (ID No. PE14051, rejected for personal reasons)
- 2012 - 2013 Alexander von Humboldt Postdoctoral Research Fellow | Karlsruhe Institute of Technology, Karlsruhe, Germany
- 2006-2007 UNESCO-IUPAC Postgraduate Course in Polymer Science | Institute of Macromolecular Chemistry, the Czech Academy of Sciences, Prague, Czechia
- 2001 Bronze Medal, 33rd International Chemistry Olympiad | Mumbai, India
- 2000 Bronze Medal, 6th Iberoamerican Chemistry Olympiad | Caracas, Venezuela
Projects
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Brush-Like Coatings Provide a Cloak of Invisibility to Titanium Implants
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https://doi.org/10.1002/mabi.202300434 | Macromolecular Bioscience | 2023 | |
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Glycan-Driven Formation of Raft-Like Domains with Hierarchical Periodic Nanoarrays on Dendrimersome Synthetic Cells
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https://doi.org/10.1021/acs.biomac.3c01027 | Biomacromolecules | 2023 | |
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Green Solvent-Based Antifouling Polymer Brushes Demonstrate Excellent Hemocompatibility
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https://doi.org/10.1021/acs.langmuir.3c02765 | Langmuir | 2023 | |
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Self-Assembly of Glycerol-Amphiphilic Janus Dendrimers Amplifies and Indicates Principles for the Selection of Stereochemistry by Biological Membranes
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https://doi.org/10.1021/jacs.3c00389 | Journal of the American Chemical Society | 2023 | |
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Synthetic Evolution of a Supramolecular Harpooning Mechanism to Immobilize Vesicles at Antifouling Interfaces
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https://doi.org/10.1002/macp.202300306 | Macromolecular Chemistry and Physics | 2023 | |
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Tackling the Root Cause of Surface-Induced Coagulation: Inhibition of Fxii Activation to Mitigate Coagulation Propagation and Prevent Clotting
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https://doi.org/10.1002/mabi.202300321 | Macromolecular Bioscience | 2023 | |
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A Green Solvent-to-Polymer Upgrading Approach to Water-Soluble LCST Poly(N-Substituted Lactamide Acrylate)s
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https://doi.org/10.1039/D2GC02780A | Green Chemistry | 2022 | |
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Biointerfaces and Biopolymers
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https://doi.org/10.1002/admi.202202252 | Advanced Materials Interfaces | 2022 | |
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Brush-Like Interface on Surface-Attached Hydrogels Repels Proteins and Bacteria
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https://doi.org/10.1002/mabi.202200025 | Macromolecular Bioscience | 2022 | |
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Dendrimersome Synthetic Cells Harbor Cell Division Machinery of Bacteria
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https://doi.org/10.1002/adma.202202364 | Advanced Materials | 2022 | |
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Evaluation of Dibenzocyclooctyne and Bicyclononyne Click Reaction on Azido-Functionalized Antifouling Polymer Brushes Via Microspotting
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https://doi.org/10.1002/admi.202102325 | Advanced Materials Interfaces | 2022 | |
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Globular Hydrophilic Poly(acrylate)s by an Arborescent Grafting-from Synthesis
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https://doi.org/10.1021/acs.macromol.1c02548 | Macromolecules | 2022 |
