Dominik Söder, M.Sc.
It is Söder's goal to develop synthetic cells that can selectively engulf pathogens. He wants to understand how to control the engulfment, i.e. transport of mesoscopic objects across the membrane. For this, he utilizes protocells formed by the assembly of Janus dendrimers with receptors that can specifically bind to pathogens. The challenge is to balance the adhesive forces with the bending rigidity of the membrane and to introduce amplification mechanisms that translate a small interaction with a large effect as “eating up a bacterium”. He envisions that the basic knowledge generated in this project will serve as a basis for the design of therapeutic synthetic cells.
Dominik Söder is part of the RG Rodriguez-Emmenegger.