PhD student
Dominik Söder, M.Sc.
Research interest
It is Söder's goal to develop synthetic cells that can selectively engulf pathogens. He wants to understand how to control the engulfment, i.e. transport of mesoscopic objects across the membrane. For this, he utilizes protocells formed by the assembly of Janus dendrimers with receptors that can specifically bind to pathogens. The challenge is to balance the adhesive forces with the bending rigidity of the membrane and to introduce amplification mechanisms that translate a small interaction with a large effect as “eating up a bacterium”. He envisions that the basic knowledge generated in this project will serve as a basis for the design of therapeutic synthetic cells.
Dominik Söder is part of the RG Rodriguez-Emmenegger.
Projects
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Brush-Like Interface on Surface-Attached Hydrogels Repels Proteins and Bacteria
L. Witzdam, Y. L. Meurer, M. Garay-Sarmiento, M. Vorobii, D. Söder, J. Quandt, T. Haraszti and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202200025 | Macromolecular Bioscience | 2022 | |
|
Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life
A. M. Wagner, J. Quandt, D. Söder, M. Garay-Sarmiento, A. Joseph, V. S. Petrovskii, L. Witzdam, T. Hammoor, P. Steitz, T. Haraszti, I. I. Potemkin, N. Y. Kostina, A. Herrmann and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/advs.202200617 | Advanced Science | 2022 | |
|
Zwitterionic Dendrimersomes: A Closer Xenobiotic Mimic of Cell Membranes
A. Joseph, A. M. Wagner, M. Garay-Sarmiento, M. Aleksanyan, T. Haraszti, D. Söder, V. N. Georgiev, R. Dimova, V. Percec and C. Rodriguez-Emmenegger
|
https://doi.org/10.1002/adma.202206288 | Advanced Materials | 2022 | |
|
Enhanced Concanavalin A Binding to Preorganized Mannose Nanoarrays in Glycodendrimersomes Revealed Multivalent Interactions
N. Yu. Kostina, D. Söder, T. Haraszti, Q. Xiao, K. Rahimi, B. E. Partridge, M. L. Klein, V. Percec and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/anie.202100400 | Angewandte Chemie International Edition | 2021 | |
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Rapid and Oriented Immobilization of Laccases on Electrodes via a Methionine-Rich Peptide
H. Cui, L. Zhang, D. Söder, X. Tang, M. D. Davari and U. Schwaneberg
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https://doi.org/10.1021/acscatal.0c05490 | ACS Catalysis | 2021 | |
|
Unraveling the Mechanism and Kinetics of Binding of an LCI-eGFP-Polymer for Antifouling Coatings
D. Söder, M. Garay-Sarmiento, K. Rahimi, F. Obstals, S. Dedisch, T. Haraszti, M. D. Davari, F. Jakob, C. Heß, U. Schwaneberg and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202100158 | Macromolecular Bioscience | 2021 | |
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Nanovesicles displaying functional linear and branched oligomannose self-assembled from sequence-defined Janus glycodendrimers
Q. Xiao, M. Delbianco, S. E. Sherman, A. M. Reveron Perez, P. Bharate, A. Pardo-Vargas, C. Rodriguez-Emmenegger, N. Y. Kostina, K. Rahimi, D. Söder, M. Möller, M. L. Klein, P. H. Seeberger and V. Percec
|
https://doi.org/10.1073/pnas.2003938117 | Proceedings of the National Academy of Sciences of the United States of America | 2020 | |
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Antifouling Microparticles To Scavenge Lipopolysaccharide from Human Blood Plasma
M. K. Vorobii, N. Y.; Rahimi, K.; Grama, S.; Soder, D.; Pop-Georgievski, O.; Sturcova, A.; Horak, D.; Grottke, O.; Singh, S.; Rodriguez-Emmenegger, C.
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https://www.doi.org/10.1021/acs.biomac.8b01583 | Biomacromolecules | 2019 |