Prof. Dr. César Rodriguez-Emmenegger
The research program of the Rodriguez-Emmenegger group focuses in the development of synthetic and biohybrid adaptive interfaces able to interact with the environment drawing inspiration in the way living systems interact and communicate. The group's overarching goal is to understand how to balance the overall repellency with specific multivalent and cooperative attractive interactions to develop superselectivity at interfaces and to translate this to the medical field. Toward this aim synthetic polymer and supramolecular chemistry, physical chemistry, biophysics, and engineering converge in a highly interdisciplinary team. In particular the Emmenegger group is interested in synthesis of macromolecules with precise chemical composition, architecture and topology. These macromolecules are used to study and develop antifouling, antimicrobial surfaces, coatings that interact with blood and modulate uncontrolled coagulation, as well as active synthetic cells.
César Rodriguez-Emmenegger's publications via ORCID
César Rodriguez-Emmenegger's publications via google scholar
Curriculum Vitae
César was born in Salto, in the north of Uruguay. After studying Chemical Engineering (2001—2006) in the Universidad de la Republica he was awarded a research UNESCO-IUPAC internship (2006-2007) in the Institute of Macromolecular Chemistry in Prague where he got hooked in the topic of polymers and biointerfaces. There he pursued his Ph.D. in Biophysics, Chemical and Macromolecular Physics under the supervision of Dr. E. Brynda and Prof. A. Bologna-Alles (2007—2012) working on optical biosensors and antifouling surfaces. Following a postdoctoral research at the group of Prof. C. Barner-Kowollik (Alexander von Humboldt postdoctoral fellowship, 2012-2013), and research stays in Melville Laboratory in Cambridge (Prof. W.T.S. Huck, 2009), University of Pennsylvania (Prof. V. Percec, 2013, 2015) and Pasteur Institute in Lille (Prof. Lafont, 2015), César returned to Prague to start his independent group supported by a Junior Grant from GACR. In January 2016, his group joined DWI and expanded the research to adaptive interfaces and synthetic cells.
Selected professional functions, honors and awards
- 2020 Innovation Sprint RWTH
- 2015 Polymer Chemistry Emerging Investigators 2015 | Royal Society of Chemistry, UK
- 2014 Japan Society for the Promotin of Science, Postdoctoral Fellowship for North Americam and European Researches (ID No. PE14051, rejected for personal reasons)
- 2012 - 2013 Alexander von Humboldt Postdoctoral Research Fellow | Karlsruhe Institute of Technology, Karlsruhe, Germany
- 2006-2007 UNESCO-IUPAC Postgraduate Course in Polymer Science | Institute of Macromolecular Chemistry, the Czech Academy of Sciences, Prague, Czechia
- 2001 Bronze Medal, 33rd International Chemistry Olympiad | Mumbai, India
- 2000 Bronze Medal, 6th Iberoamerican Chemistry Olympiad | Caracas, Venezuela
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Oriented immobilization of Pep19-2.5 on antifouling brushes suppresses the development of Staphylococcus aureus biofilms
M. Vorobii, R. Teixeira-Santos, L. C. Gomes, M. Garay-Sarmiento, A. M. Wagner, F. J. Mergulhão and C. Rodriguez-Emmenegger
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https://doi.org/10.1016/j.porgcoat.2021.106609 | Progress in Organic Coatings | 2021 | |
Photoinduced Upgrading of Lactic Acid-Based Solvents to Block Copolymer Surfactants
N. Bensabeh, A. Moreno, A. Roig, M. Rahimzadeh, K. Rahimi, J. C. Ronda, V. Cádiz, M. Galià, V. Percec, C. Rodriguez-Emmenegger and G. Lligadas
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https://doi.org/10.1021/acssuschemeng.9b06599 | ACS Sustainable Chemistry & Engineering | 2019 | |
Plasmonic Hepatitis B Biosensor for the Analysis of Clinical Saliva
T. Riedel, S. Hageneder, F. Surman, O. Pop-Georgievski, C. Noehammer, M. Hofner, E. Brynda, C. Rodriguez-Emmenegger and J. Dostalek
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https://www.doi.org/10.1021/acs.analchem.6b04432 | Analytical Chemistry | 2017 | |
Polymer Brush Collapse under Shear Flow
A. Korolkovas, C. Rodriguez-Emmenegger, A. D. Pereira, A. Chenneviere, F. Restagno, M. Wolff, F. A. Adlmann, A. J. C. Dennison and P. Gutfreund
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https://www.doi.org/10.1021/acs.macromol.6b02525 | Macromolecules | 2017 | |
Polymer Brush-Functionalized Chitosan Hydrogels as Antifouling Implant Coatings
I. Buzzacchera, M. Vorobii, N. Y. Kostina, A. D. Pereira, T. Riedel, M. Bruns, W. Ogieglo, M. Moller, C. J. Wilson and C. Rodriguez-Emmenegger
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https://www.doi.org/10.1021/acs.biomac.7b00516 | Biomacromolecules | 2017 | |
Screening Libraries of Amphiphilic Janus Dendrimers Based on Natural Phenolic Acids to Discover Monodisperse Unilamellar Dendrimersomes
I. Buzzacchera, Q. Xiao, H. Han, K. Rahimi, S. D. Li, N. Y. Kostina, B. J. Toebes, S. E. Wilner, M. Moller, C. Rodriguez-Emmenegger, T. Baumgart, D. A. Wilson, C. J. Wilson, M. L. Klein and V. Percec
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https://www.doi.org/10.1021/acs.biomac.8b01405 | Biomacromolecules | 2019 | |
Self-Assembly of Glycerol-Amphiphilic Janus Dendrimers Amplifies and Indicates Principles for the Selection of Stereochemistry by Biological Membranes
D. Zhang, Q. Xiao, M. Rahimzadeh, M. Liu, C. Rodriguez-Emmenegger, Y. Miyazaki, W. Shinoda and V. Percec
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https://doi.org/10.1021/jacs.3c00389 | Journal of the American Chemical Society | 2023 | |
Sensitive and rapid detection of aflatoxin M1 in milk utilizing enhanced SPR and p(HEMA) brushes
A. Karczmarczyk, M. Dubiak-Szepietowska, M. Vorobii, C. Rodriguez-Emmenegger, J. Dostalek and K. H. Feller
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https://www.doi.org/10.1016/j.bios.2016.02.061 | Biosensors & Bioelectronics | 2016 | |
Surface plasmon resonance-based aptasensor for direct monitoring of thrombin in a minimally processed human blood
D. Kotlarek, F. Curti, M. Vorobii, R. Corradini, M. Careri, W. Knoll, C. Rodriguez-Emmenegger and J. Dostálek
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https://doi.org/10.1016/j.snb.2020.128380 | Sensors and Actuators B-Chemical | 2020 | |
Synthetic Evolution of a Supramolecular Harpooning Mechanism to Immobilize Vesicles at Antifouling Interfaces
J. Englert, L. Witzdam, D. Söder, M. Garay-Sarmiento, A. Joseph, A. M. Wagner and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/macp.202300306 | Macromolecular Chemistry and Physics | 2023 | |
Tackling the Root Cause of Surface-Induced Coagulation: Inhibition of Fxii Activation to Mitigate Coagulation Propagation and Prevent Clotting
L. Witzdam, B. Vosberg, K. Große-Berkenbusch, S. Stoppelkamp, H. P. Wendel and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202300321 | Macromolecular Bioscience | 2023 | |
The potential advantages of using a poly(HPMA) brush in urinary catheters: effects on biofilm cells and architecture
P. Alves, L. C. Gomes, M. Vorobii, C. Rodriguez-Emmenegger and F. J. Mergulhão
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https://doi.org/10.1016/j.colsurfb.2020.110976 | Colloids and Surfaces B: Biointerface | 2020 |