Postdoc
Dr. Nina Kostina
Forschungsinteresse
Inspiriert von den faszinierenden Eigenschaften der Zellmembran, unzählige biologische Funktionen zu erfüllen, möchte Nina neue vollsynthetische Modelle der Zellmembran aufbauen. Sie konzentriert sich auf die Entwicklung neuer Konzepte für Vesikel, deren Eigenschaften durch die molekulare Struktur der membranbildenden Moleküle - Amphiphile - gesteuert werden können. Sie möchte diese Vesikel nutzen, um komplexe zelluläre Eigenschaften zu untersuchen und grundlegende Abläufe zu programmieren, die es nicht zwangsweise schon in der Natur geben muss.
Nina Kostina ist Teil der AG Rodriguez-Emmenegger.
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Design-functionality relationships for adhesion/growth-regulatory galectins
A. K. Ludwig, M. Michalak, Q. Xiao, U. Gilles, F. J. Medrano, H. Y. Ma, F. G. FitzGerald, W. D. Hasley, A. Melendez-Davila, M. Liu, K. Rahimi, N. Y. Kostina, C. Rodriguez-Emmenegger, M. Moller, I. Lindner, H. Kaltner, M. Cudic, D. Reusch, J. Kopitz, A. Romero, S. Oscarson, M. L. Klein, H. J. Gabius and V. Percec
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https://www.doi.org/10.1073/pnas.1813515116 | Proceedings of the National Academy of Sciences of the United States of America | 2019 | |
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Direct Visualization of Vesicle Disassembly and Reassembly Using Photocleavable Dendrimers Elucidates Cargo Release Mechanisms
S. Li, B. Xia, B. Javed, W. D. Hasley, A. Melendez-Davila, M. Liu, M. Kerzner, S. Agarwal, Q. Xiao, P. Torre, J. G. Bermudez, K. Rahimi, N. Y. Kostina, M. Möller, C. Rodriguez-Emmenegger, M. L. Klein, V. Percec and M. C. Good
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https://doi.org/10.1021/acsnano.0c02912 | ACS Nano | 2020 | |
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Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids
P. Torre, Q. Xiao, I. Buzzacchera, S. E. Sherman, K. Rahimi, N. Y. Kostina, C. Rodriguez-Emmenegger, M. Moller, C. J. Wilson, M. L. Klein, M. C. Good and V. Percec
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https://www.doi.org/10.1073/pnas.1904868116 | Proc Natl Acad Sci U S A | 2019 | |
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Encoding biological recognition in a bicomponent cell-membrane mimic
C. Rodriguez-Emmenegger, Q. Xiao, N. Y. Kostina, S. E. Sherman, K. Rahimi, B. E. Partridge, S. D. Li, D. Sahoo, A. M. R. Perez, I. Buzzacchera, H. Han, M. Kerzner, I. Malhotra, M. Moller, C. J. Wilson, M. C. Good, M. Goulian, T. Baumgart, M. L. Klein and V. Percec
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https://www.doi.org/10.1073/pnas.1821924116 | Proceedings of the National Academy of Sciences of the United States of America | 2019 | |
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Enhanced Concanavalin A Binding to Preorganized Mannose Nanoarrays in Glycodendrimersomes Revealed Multivalent Interactions
N. Yu. Kostina, D. Söder, T. Haraszti, Q. Xiao, K. Rahimi, B. E. Partridge, M. L. Klein, V. Percec and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/anie.202100400 | Angewandte Chemie International Edition | 2021 | |
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Improving Hemocompatibility: How Can Smart Surfaces Direct Blood To Fight against Thrombi
F. Obstals, L. Witzdam, M. Garay-Sarmiento, N. Y. Kostina, J. Quandt, R. Rossaint, S. Singh, O. Grottke and C. Rodriguez-Emmenegger
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https://doi.org/10.1021/acsami.1c01079 | ACS Applied Materials & Interfaces | 2021 | |
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Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life
A. M. Wagner, J. Quandt, D. Söder, M. Garay-Sarmiento, A. Joseph, V. S. Petrovskii, L. Witzdam, T. Hammoor, P. Steitz, T. Haraszti, I. I. Potemkin, N. Y. Kostina, A. Herrmann and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/advs.202200617 | Advanced Science | 2022 | |
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Membrane-Mimetic Dendrimersomes Engulf Living Bacteria via Endocytosis
N. Y. Kostina, K. Rahimi, Q. Xiao, T. Haraszti, S. Dedisch, J. P. Spatz, U. Schwaneberg, M. L. Klein, V. Percec, M. Moller and C. Rodriguez-Emmenegger
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https://www.doi.org/10.1021/acs.nanolett.9b02349 | Nano Lett | 2019 | |
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Nanovesicles displaying functional linear and branched oligomannose self-assembled from sequence-defined Janus glycodendrimers
Q. Xiao, M. Delbianco, S. E. Sherman, A. M. Reveron Perez, P. Bharate, A. Pardo-Vargas, C. Rodriguez-Emmenegger, N. Y. Kostina, K. Rahimi, D. Söder, M. Möller, M. L. Klein, P. H. Seeberger and V. Percec
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https://doi.org/10.1073/pnas.2003938117 | Proceedings of the National Academy of Sciences of the United States of America | 2020 | |
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Screening Libraries of Amphiphilic Janus Dendrimers Based on Natural Phenolic Acids to Discover Monodisperse Unilamellar Dendrimersomes
I. Buzzacchera, Q. Xiao, H. Han, K. Rahimi, S. D. Li, N. Y. Kostina, B. J. Toebes, S. E. Wilner, M. Moller, C. Rodriguez-Emmenegger, T. Baumgart, D. A. Wilson, C. J. Wilson, M. L. Klein and V. Percec
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https://www.doi.org/10.1021/acs.biomac.8b01405 | Biomacromolecules | 2019 | |
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Unraveling topology-induced shape transformations in dendrimersomes
N. Y. Kostina, A. M. Wagner, T. Haraszti, K. Rahimi, Q. Xiao, M. L. Klein, V. Percec and C. Rodriguez-Emmenegger
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https://doi.org/10.1039/D0SM01097A | Soft Matter | 2020 | |
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Zwitterionic Functionalizable Scaffolds with Gyroid Pore Architecture for Tissue Engineering
N. Y. Kostina, S. Blanquer, O. Pop-Georgievski, K. Rahimi, B. Dittrich, A. Hocherl, J. Michalek, D. W. Grijpma and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.201800403 | Macromolecular Bioscience | 2019 |