PhD student
Lena Witzdam, M.Sc.
Research interest
Lena Witzdam works on the development of adaptive hemocompatible coatings for medical applications. The coatings are engineered to passively prevent thrombus formation by modification with polymer brushes but are also able to communicate with blood and direct it in a self-regulated manner. The inspiration for this is nature and the mechanisms used by the body to achieve a balance between clotting and fibrinolysis.
Lena Witzdam is part of the RG Rodriguez-Emmenegger.
Projects
Publications
Titel/Autoren | DOI-LINK | Magazine | Jahre | |
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Tackling the Root Cause of Surface-Induced Coagulation: Inhibition of Fxii Activation to Mitigate Coagulation Propagation and Prevent Clotting
L. Witzdam, B. Vosberg, K. Große-Berkenbusch, S. Stoppelkamp, H. P. Wendel and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202300321 | Macromolecular Bioscience | 2023 | |
Synthetic Evolution of a Supramolecular Harpooning Mechanism to Immobilize Vesicles at Antifouling Interfaces
J. Englert, L. Witzdam, D. Söder, M. Garay-Sarmiento, A. Joseph, A. M. Wagner and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/macp.202300306 | Macromolecular Chemistry and Physics | 2023 | |
Kill&Repel Coatings: The Marriage of Antifouling and Bactericidal Properties to Mitigate and Treat Wound Infections
M. Garay-Sarmiento, L. Witzdam, M. Vorobii, C. Simons, N. Herrmann, A. de los Santos Pereira, E. Heine, I. El-Awaad, R. Lütticken, F. Jakob, U. Schwaneberg and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/adfm.202106656 | Advanced Functional Materials | 2021 | |
Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life
A. M. Wagner, J. Quandt, D. Söder, M. Garay-Sarmiento, A. Joseph, V. S. Petrovskii, L. Witzdam, T. Hammoor, P. Steitz, T. Haraszti, I. I. Potemkin, N. Y. Kostina, A. Herrmann and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/advs.202200617 | Advanced Science | 2022 | |
Interactive Hemocompatible Nanocoating to Prevent Surface-Induced Coagulation in Medical Devices
J. Quandt, M. Garay-Sarmiento, L. Witzdam, J. Englert, Y. Rutsch, C. Stöcker, F. Obstals, O. Grottke and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/admi.202201055 | Advanced Materials Interfaces | 2022 | |
Improving Hemocompatibility: How Can Smart Surfaces Direct Blood To Fight against Thrombi
F. Obstals, L. Witzdam, M. Garay-Sarmiento, N. Y. Kostina, J. Quandt, R. Rossaint, S. Singh, O. Grottke and C. Rodriguez-Emmenegger
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https://doi.org/10.1021/acsami.1c01079 | ACS Applied Materials & Interfaces | 2021 | |
Green Solvent-Based Antifouling Polymer Brushes Demonstrate Excellent Hemocompatibility
J. Englert, M. Palà, L. Witzdam, F. Rayatdoost, O. Grottke, G. Lligadas and C. Rodriguez-Emmenegger
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https://doi.org/10.1021/acs.langmuir.3c02765 | Langmuir | 2023 | |
Brush-Like Interface on Surface-Attached Hydrogels Repels Proteins and Bacteria
L. Witzdam, Y. L. Meurer, M. Garay-Sarmiento, M. Vorobii, D. Söder, J. Quandt, T. Haraszti and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202200025 | Macromolecular Bioscience | 2022 | |
Brush-Like Coatings Provide a Cloak of Invisibility to Titanium Implants
L. Witzdam, M. Garay-Sarmiento, M. Gagliardi, Y. L. Meurer, Y. Rutsch, J. Englert, S. Philipsen, A. Janem, R. Alsheghri, F. Jakob, D. G. M. Molin, U. Schwaneberg, N. M. S. van den Akker and C. Rodriguez-Emmenegger
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https://doi.org/10.1002/mabi.202300434 | Macromolecular Bioscience | 2023 |