Postdoc
Dr. Laura Klasen
Dr. Laura Klasen's research addresses the development of 3D macroporous microgel assemblies to expand and differentiate stem cells. The main research focus is on the expansion and differentiation of induced pluripotent stem cells (iPSCs) in these macroporous assemblies to generate cardiovascular tissue. Thereby the influence of mechanical stimuli exhibited by the biomaterials on the cellular responses is analyzed. The superior motive for this research focus is the production of in vitro vascularized human heart tissue for drug testing and disease modeling.
Laura Klasen is part of the RG De Laporte.
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Differentiation and maturation of iPSC–derived motor and sensory neurospheres using biomodified PEG–based microgels
L. Klasen; C. Bastard; M. Mork; G. Romahn; J. L. Gerardo Nava; L. De Laporte
|
https://doi.org/10.64898/2026.08.19.745683 | bioRxiv | 2026 | |
|
Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High-Throughput
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte
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https://doi.org/10.1002/adma.75116 | Advanced materials | 2026 | |
|
Upscaling the Fabrication of Rod-Shaped Microgels: A Microfluidic Method Combining Step-Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels
M. Mork; N. Möhl; G. Romahn; L. Klasen; C. Bergerbit; L. De Laporte
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https://doi.org/10.1002/adma.74822 | Advanced Materials | 2026 | |
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Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids — From Sizable to High Throughput
L. Klasen, M. Mork, R. Nasehi, V. T. Krishnamurthy, K. Zeevaert, A. Babendreyer, J. Di Russo, W. Wagner, L. De Laporte
|
https://doi.org/10.1101/2025.10.20.683388 | bioRxiv Preprint | 2025 | |
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Structural guidance in 3D microgel-in-hydrogel systems to improve chondrogenesis
Julia Kamp, Alisa C. Suturin, Claudia A. Garrido, Xiaole Tong, Jietao Xu, Nicole Kops, Lea-Sophie Müller, Till Hülsmann, Laura Klasen, Tamás Haraszti, Gerjo J.V.M. van Osch, Laura De Laporte
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https://doi.org/10.64898/2025.12.19.694877 | bioRxiv | 2025 | |
|
Transformative Materials to Create 3D Functional Human Tissue Models in Vitro in a Reproducible Manner
J. L. Gerardo-Nava, J. Jansen, D. Günther, L. Klasen, A. L. Thiebes, B. Niessing, C. Bergerbit, A. A. Meyer, J. Linkhorst, M. Barth, P. Akhyari, J. Stingl, S. Nagel, T. Stiehl, A. Lampert, R. Leube, M. Wessling, F. Santoro, S. Ingebrandt, S. Jockenhoevel, A. Herrmann, H. Fischer, W. Wagner, R. H. Schmitt, F. Kiessling, R. Kramann and L. De Laporte
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https://doi.org/10.1002/adhm.202301030 | Advanced Healthcare Materials | 2023 |