Research Group Schwaneberg
The expertise of the Schwaneberg group lies in protein engineering by directed evolution and rational design. Directed evolution methodologies were awarded with the Nobel Prize in chemistry in 2018 and workgroup Schwaneberg is ranked 3rd in respect to published manuscripts (Web of Science; search term “directed evolution”). Research is organized in 5 divisions with the general goal to advance directed evolution methodologies, to discover fundamental design principles of proteins, and to perform translational research within the areas of interactive materials (focus on plant health, medicine), biocatalysis, and circular bioeconomy. Developed protein engineering strategies such as KnowVolution are used to combine computational and experimental efforts and thereby to ensure efficient protein design with minimal experimental efforts and a molecular understanding of improved properties.
Prof. Dr. Ulrich Schwaneberg
Team
Projects
Publications
| Titel/Autoren | DOI-LINK | Magazine | Jahre | |
|---|---|---|---|---|
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Bifunctional Peptides as Alternatives to Copper-Based Formulations to Control Citrus Canker
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https://doi.org/10.1007/s00253-023-12908-3 | Applied Microbiology and Biotechnology | 2024 | |
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Validated High-Throughput Screening System for Directed Evolution of Nylon-Depolymerizing Enzymes
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https://doi.org/10.1021/acssuschemeng.3c01575 | ACS Sustainable Chemistry & Engineering | 2023 | |
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Transformative Materials for Interfacial Drug Delivery
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https://doi.org/10.1002/adhm.202301062 | Advanced Healthcare Materials | 2023 | |
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Surface Engineering of Cyclodextrin Glycosyltransferase Reveals Structural Compactness and Rigidity Responsible for Enhanced Organic Solvents Resistance
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https://doi.org/10.1016/j.mcat.2023.113613 | Molecular Catalysis | 2023 | |
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Rational Design of an Artificial Ethylbenzene Hydroxylase Using a Molecular Dynamics Simulation to Enhance Enantioselectivity
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https://doi.org/10.1093/chemle/upad042 | Chemistry Letters | 2023 | |
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Novel Multienzyme Cascade for Efficient Synthesis of D-Allulose from Inexpensive Sucrose
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https://doi.org/10.1016/j.fbio.2023.103303 | Food Bioscience | 2023 | |
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Machine Learning-Assisted Engineering of Light, Oxygen, Voltage Photoreceptor Adduct Lifetime
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https://doi.org/10.1021/jacsau.3c00440 | JACS Au | 2023 | |
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Introduction of Aromatic Amino Acids in Electron Transfer Pathways Yielded Improved Catalytic Performance of Cytochrome P450s
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https://doi.org/10.1016/S1872-2067(23)64445-6 | Chinese Journal of Catalysis | 2023 | |
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Hexyl Gallate Loaded Microgels Enable Efficient Protection Against Citrus Canker
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https://doi.org/10.1002/adfm.202305646 | Advanced Functional Materials | 2023 | |
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Fhua: From Iron-Transporting Transmembrane Protein to Versatile Scaffolds through Protein Engineering
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https://doi.org/10.1021/acs.accounts.3c00060 | Accounts of Chemical Research | 2023 | |
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Engineering of Substrate Tunnel of P450 Cyp116b3 Though Machine Learning
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https://doi.org/10.3390/catal13081228 | Catalysts | 2023 | |
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Engineering All-Round Cellulase for Bioethanol Production
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https://doi.org/10.1021/acssynbio.3c00289 | ACS Synthetic Biology | 2023 |